1204518-00-2 Usage
Description
(4-chlorophenyl)(mesityl)iodonium trifluoromethanesulfonate is a complex chemical compound characterized by a trifluoromethanesulfonate group attached to an iodonium center, which is bonded to a 4-chlorophenyl and a mesityl group. (4-chlorophenyl)(mesityl)iodonium trifluoromethanesulfonate is known for its unique reactivity and stability, making it a valuable tool in synthetic organic chemistry.
Uses
Used in Synthetic Organic Chemistry:
(4-chlorophenyl)(mesityl)iodonium trifluoromethanesulfonate is used as a source of electrophilic iodine(III) for the synthesis of complex organic molecules and the functionalization of aromatic compounds. Its mild and selective oxidizing properties, along with its ability to transfer an iodonium group to other molecules, make it a versatile reagent in this field.
Used in Medicinal Chemistry:
In the pharmaceutical industry, (4-chlorophenyl)(mesityl)iodonium trifluoromethanesulfonate is used as a precursor for the preparation of various aryl-iodonium salts. These salts have potential applications in the development of new drugs and therapeutic agents.
Used in Materials Science:
(4-chlorophenyl)(mesityl)iodonium trifluoromethanesulfonate is also utilized in materials science for the synthesis of novel materials with specific properties, such as conductivity or magnetism, which can be beneficial in various technological applications.
Used in Biochemical Research:
(4-chlorophenyl)(mesityl)iodonium trifluoromethanesulfonate serves as a valuable tool in biochemical research, where it can be employed to study the reactivity and interactions of various biomolecules, contributing to a better understanding of biological processes and the development of targeted therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 1204518-00-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,0,4,5,1 and 8 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1204518-00:
(9*1)+(8*2)+(7*0)+(6*4)+(5*5)+(4*1)+(3*8)+(2*0)+(1*0)=102
102 % 10 = 2
So 1204518-00-2 is a valid CAS Registry Number.
1204518-00-2Relevant articles and documents
Refining boron-iodane exchange to access versatile arylation reagents
Karandikar, Shubhendu S.,Stuart, David R.
supporting information, p. 1211 - 1214 (2022/02/03)
Aryl(Mes)iodonium salts, which are multifaceted aryl transfer reagents, are synthesized via boron-iodane exchange. Modification to both the nucleophilic (aryl boron) and electrophilic (mesityl-λ3-iodane) reaction components results in improved yield and faster reaction time compared to previous conditions. Mechanistic studies reveal a pathway that is more like transmetallation than SEAr.
Synthesis of Diverse Aryliodine(III) Reagents by Anodic Oxidation?
Zu, Bing,Ke, Jie,Guo, Yonghong,He, Chuan
supporting information, p. 627 - 632 (2021/02/12)
An anodic oxidation enabled synthesis of hypervalent iodine(III) reagents from aryl iodides is demonstrated. Under mild electrochemical conditions, a range of aryliodine(III) reagents including iodosylarenes, (difunctionaliodo)arenes, benziodoxoles and diaryliodonium salts can be efficiently synthesized and derivatized in good to excellent yields with high selectivity. As only electrons serve as the oxidation reagents, this method offers a more straightforward and sustainable manner avoiding the use of expensive or hazardous chemical oxidants.
Flow Synthesis of Diaryliodonium Triflates
Laudadio, Gabriele,Gemoets, Hannes P. L.,Hessel, Volker,No?l, Timothy
, p. 11735 - 11741 (2017/11/24)
A safe and scalable synthesis of diaryliodonium triflates was achieved using a practical continuous-flow design. A wide array of electron-rich to electron-deficient arenes could readily be transformed to their respective diaryliodonium salts on a gram scale, with residence times varying from 2 to 60 s (44 examples).
