120627-94-3

Basic information

• Product Name: 1-(Dimethyl-phenyl-silanyl)-butan-1-one
• Synonyms: 1-(Dimethyl-phenyl-silanyl)-butan-1-one
• CAS NO: 120627-94-3
• Molecular Weight: 206.36
• Mol File: 120627-94-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-(Dimethyl-phenyl-silanyl)-butan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(Dimethyl-phenyl-silanyl)-butan-1-one(120627-94-3)
• EPA Substance Registry System: 1-(Dimethyl-phenyl-silanyl)-butan-1-one(120627-94-3)

Safety Data

• Hazardous Substances Data: 120627-94-3(Hazardous Substances Data)

Upstream product

• 96720-38-6 (E)-1-(phenyldimethylsilyl)-2-buten-1-ol 
• 541-35-5 butanamide 
• 3839-31-4 dimethyl(phenyl)silyllithium 
• 141-75-3 butyryl chloride 
• 768-33-2 phenyldimethylsilyl chloride 

Downstream Products

• 185844-36-4 (Z)-1-[dimethyl(phenyl)silyl]but-1-enethiol 
• 80279-07-8 (E)-(hex-3-en-3-yl)dimethyl(phenyl)silane 
• 185844-38-6 Dimethyl-((Z)-1-methylsulfanyl-but-1-enyl)-phenyl-silane 
• 185844-51-3 ((Z)-1-Methanesulfonyl-but-1-enyl)-dimethyl-phenyl-silane 
• 185844-42-2 3-[(Z)-1-(Dimethyl-phenyl-silanyl)-but-1-enylsulfanyl]-propionic acid ethyl ester 
• 146758-90-9 1-dimethyl(phenyl)silylbut-1-yne 

Relevant articles and documents

A synthesis of enantiomerically enriched propargyl silanes

Reduction of ethyl 3-methyl-, 3-isopropyl- and 3-n-pentyl-3-[dimethyl(phenyl)silyl]propanoates 4 with DIBAL to the aldehydes 5, enol trifluoromethanesulfonate (triflate) formation using trifluoromethanesulfonic (triflic) anhydride and 2,6-di-tert-butylpyridine, and elimination using LDA, gives the propargyl silanes 8. The esters 4 could also be prepared enantiomerically enriched (11), and the final products are the enantiomerically enriched propargyl (homochiral) silanes 14.

A regiodefined synthesis of α-trimethylsilyl ketones catalyzed by rhodium(I) hydride complex

Regiodefined synthesis of α-trimethylsilyl ketones is attained by one of three different routes: isomerization of β-trimethylsilyl allyl alcohols (route A), isomerization of β'-trimethylsilyl allyl alcohols (route B), and dehydrogenation of β-trimethylsil