120671-12-7

Basic information

• Product Name: 1-benzyl-2-(ethoxycarbonylmethylene)-2,3,4,5-tetrahydroimidazole
• Synonyms: 1-benzyl-2-(ethoxycarbonylmethylene)-2,3,4,5-tetrahydroimidazole
• CAS NO: 120671-12-7
• Molecular Weight: 246.309
• Mol File: 120671-12-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-benzyl-2-(ethoxycarbonylmethylene)-2,3,4,5-tetrahydroimidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-2-(ethoxycarbonylmethylene)-2,3,4,5-tetrahydroimidazole(120671-12-7)
• EPA Substance Registry System: 1-benzyl-2-(ethoxycarbonylmethylene)-2,3,4,5-tetrahydroimidazole(120671-12-7)

Safety Data

• Hazardous Substances Data: 120671-12-7(Hazardous Substances Data)

Upstream product

• 4152-09-4 N-benzylethylenediamine 
• 95271-71-9 1-benzyl-2-methyl-4,5-dihydroimidazole hydrochloride 
• 55244-11-6 ethyl cyanoacetimidate hydrochloride 
• 27317-59-5 Ethyl 3-ethoxy-3-iminopropionate 
• 6096-36-2 1-benzyl-2-methyl-4,5-dihydro-1H-imidazole 
• 105-58-8 Diethyl carbonate 

Downstream Products

• 126812-01-9 (1-Benzyl-4,5-dihydro-1H-imidazol-2-yl)-(5-oxo-tetrahydro-furan-3-yl)-acetic acid ethyl ester 
• 126812-15-5 1-Benzyl-6,7-dimethyl-1,2,3,7-tetrahydro-imidazo[1,2-a]pyridine-8-carboxylic acid ethyl ester 
• 120671-14-9 1-Benzyl-7-methyl-5-oxo-1,2,3,5,6,7-hexahydro-imidazo[1,2-a]pyridine-8-carboxylic acid ethyl ester 
• 120671-15-0 1-Benzyl-5-oxo-7-phenyl-1,2,3,5,6,7-hexahydro-imidazo[1,2-a]pyridine-8-carboxylic acid ethyl ester 
• 120671-17-2 1-Benzyl-8a-hydroxy-7-methyl-5-oxo-octahydro-imidazo[1,2-a]pyridine-8-carboxylic acid ethyl ester 
• 120671-20-7 1-Benzyl-8a-hydroxy-5-oxo-octahydro-imidazo[1,2-a]pyridine-8-carboxylic acid ethyl ester 
• 134432-16-9 ethyl 1-(1-benzyl-4,5-dihydroimidazol-2-yl)cyclohexanecarboxylate 
• 126812-08-6 6-(1-Benzyl-4,5-dihydro-1H-imidazol-2-yl)-hexan-3-one 
• 126812-11-1 4-(1-Benzyl-4,5-dihydro-1H-imidazol-2-yl)-butyronitrile 
• 126812-07-5 5-(1-Benzyl-4,5-dihydro-1H-imidazol-2-yl)-pentan-2-one 
• 134432-20-5 1-benzyl-2-cyclopentyl-4,5-dihydroimidazole 
• 77889-19-1 1-benzyl-2-propyl-4,5-dihydroimidazole 
• 120671-16-1 1-benzyl-8-ethoxycarbonyl-1,2,3,5-tetrahydroimidazo[1,2-a]pyridin-5-one 
• 439118-93-1 1-benzyl-2-(1-ethoxycarbonyl-3-ethoxycarbonylprop-2-enylidene)-2,3,4,5-tetrahydroimidazole 

Relevant articles and documents

The aza-ene or the Michael addition? Examination of an unusual substituent effect on the reaction of heterocyclic ketene aminals with ethyl propiolate

Heterocyclic ketene aminals having at least one secondary amino group underwent the aza-ene reaction with ethyl propiolate under various conditions to yield the corresponding adducts, which were readily transformed into the δ-lactam fused heterocyclic products with or without the aid of sodium ethoxide in refluxing ethanol, while the ester- and cyano-substituted tertiary enediamines acted as the strong Michael donor to add to ethyl propiolate in a polar or a protic solvent. The unusual substituent effect on the reactivity and mechanism was discussed.