6096-36-2

Basic information

• Product Name: 1H-Imidazole, 4,5-dihydro-2-methyl-1-(phenylmethyl)-
• Synonyms: 1H-Imidazole, 4,5-dihydro-2-methyl-1-(phenylmethyl)-;1-Benzyl-2-methyl-2-imidazoline;1-Benzyl-2-methyl-4,5-dihydroimidazole;1-Benzyl-2-Methyl-4,5-dihydro-1H-iMidazole
• CAS NO: 6096-36-2
• Molecular Formula: C₁₁H₁₄N₂
• Molecular Weight: 174
• Mol File: 6096-36-2.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 319℃
• Flash Point: 147℃
• Appearance: /
• Density: 1.04
• Storage Temp.: 2-8°C
• PKA: 11.37±0.60(Predicted)
• CAS DataBase Reference: 1H-Imidazole, 4,5-dihydro-2-methyl-1-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Imidazole, 4,5-dihydro-2-methyl-1-(phenylmethyl)-(6096-36-2)
• EPA Substance Registry System: 1H-Imidazole, 4,5-dihydro-2-methyl-1-(phenylmethyl)-(6096-36-2)

Safety Data

• Hazardous Substances Data: 6096-36-2(Hazardous Substances Data)

Usage

General Description

1H-Imidazole, 4,5-dihydro-2-methyl-1-(phenylmethyl)- is a chemical compound with the molecular formula C13H16N2. It is a derivative of imidazole, which is a five-membered heterocyclic ring containing two nitrogen atoms. The "4,5-dihydro-2-methyl-1-(phenylmethyl)-" group attached to the imidazole ring indicates the specific structure of this compound. This chemical is used in various pharmaceutical and biological applications, including as a building block for the synthesis of organic compounds, and as a ligand in coordination chemistry. Its unique structure and properties make it a valuable and versatile compound in the field of organic synthesis and medicinal chemistry.

Upstream product

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• 2208-07-3 ethyl acetimidate hydrochloride 
• 61764-86-1 1-benzyl-4,5-dihydroimidazole 
• 74-88-4 methyl iodide 
• 120671-12-7 1-benzyl-2-(ethoxycarbonylmethylene)-2,3,4,5-tetrahydroimidazole 
• 100-44-7 benzyl chloride 
• 77-78-1 dimethyl sulfate 
• 79-24-3 Nitroethane 

Downstream Products

• 77889-22-6 1-benzyl-2-isobutyl-4,5-dihydroimidazole 
• 77889-20-4 1-benzyl-2-pentyl-4,5-dihydroimidazole 
• 77889-23-7 1-benzyl-2-(4-methylpent-3-enyl)-4,5-dihydroimidazole 
• 95271-73-1 1-benzyl-2-(2-hydroxyhept-1-enyl)-4,5-dihydroimidazole 
• 128993-55-5 1-benzyl-2-octyl-4,5-dihydroimidazole 
• 77889-21-5 1-benzyl-2-nonyl-4,5-dihydroimidazole 
• 121179-42-8 1-Benzyl-2-((Z)-2-methyl-hex-1-enyl)-4,5-dihydro-1H-imidazole 
• 121179-41-7 1-Benzyl-2-((E)-2-methyl-hex-1-enyl)-4,5-dihydro-1H-imidazole 
• 129884-21-5 1-benzyl-2-(7-bromo-2-hydroxyhept-1-enyl)-4,5-dihydroimidazole 
• 129884-23-7 (Z)-1-(1-Benzyl-4,5-dihydro-1H-imidazol-2-yl)-7-iodo-hept-1-en-2-ol 
• 129884-22-6 1-benzyl-2-(6-methoxycarbonylhexyl)-4,5-dihydroimidazole 
• 129884-27-1 1-benzyl-2-<6-(4-methyl-2,6,7-trioxabicyclo<2.2.2>oct-1-yl)-hexyl>-4,5-dihydroimidazole 
• 77889-24-8 1-benzyl-2-phenethyl-4,5-dihydro-1H-imidazole 
• 77889-19-1 1-benzyl-2-propyl-4,5-dihydroimidazole 

Relevant articles and documents

N-alkylation of 2-methyl-2-imidazolines by phase transfer catalysis without solvent

1-Alkyl-2-methyl-2-imidazolines were obtained in good to excellent yields by alkylation of 2-methyl-2-imidazoline with organic halides in the presence of phase transfer catalysis and absence of solvent.

Electrophilically activated nitroalkanes in reaction with aliphatic diamines en route to imidazolines

A novel synthetic methodology for the assembly of imidazolines via an unusual reaction between nitroalkanes and aliphatic 1,2-diamines in the presence of phosphorous acid is described. In contrast to the related highly efficient preparation of benzimidazoles from aromatic amines, this process represents a major synthetic challenge and for a long time was elusive. Analysis of the method limitations is provided.

Alkylation of an imidazolidine enaminoester: A new sequence for the c(α)-alkylation of 4,5-dihydroimidazoles

1-Benzyl-2-(ethoxycarbonyllmethylene)-2,3,4,5-tetrahydroimidazole undergoes preferred C-alkylation with halogenonakanes, dihalogenoalkanes and epoxides: subsequent removal of of the ethoxycarbonyl group provides a new route to 2-alkyl-4,5-dihydroimidazoles. 1,3-Dihalogenoalkanes afford imidazo[1,2-a]pyridines via C,N-dialkylation.