77889-22-6Relevant articles and documents
Dihydroimidazoles in Synthesis: C-Alkylation of 1-Benzyl-2-(α-lithioalkyl)-4,5-dihydroimidazoles and a Synthesis of Alkanoic Acids
Anderson, Michael W.,Jones, Raymond C. F.,Saunders, John
, p. 205 - 210 (2007/10/02)
1-Benzyl-2-alkyl-4,5-dihydroimidazoles have been (laterally) metallated and C-alkylated by reaction with alkyl halides and an epoxide; intramolecular C-alkylation has led to a tetrahydro-5H-pyrroloimidazole.Hydrolysis of the 4,5-dihydroimidazoles to produce alkanoic acids completes a homologation sequence.