77889-24-8Relevant articles and documents
A Novel Class of Dopamine D4Receptor Ligands Bearing an Imidazoline Nucleus
Mammoli, Valerio,Bonifazi, Alessandro,Dal Ben, Diego,Giannella, Mario,Giorgioni, Gianfabio,Piergentili, Alessandro,Pigini, Maria,Quaglia, Wilma,Thomas, Ajiroghene,Newman, Amy H.,Ferré, Sergi,Sanchez-Soto, Marta,Keck, Thomas M.,Del Bello, Fabio
, p. 1819 - 1828 (2016)
Over the years, the 2-substituted imidazoline nucleus has been demonstrated to be a bioversatile structural motif. In this study, novel imidazoline derivatives bearing a 3- and/or 4-hydroxy- or methoxy-substituted phenyl ring, linked by an ethylene bridge
Alkylation of an imidazolidine enaminoester: A new sequence for the c(α)-alkylation of 4,5-dihydroimidazoles
Jones, Raymond C. F.,Patel, Pravin,Hirst, Simon C.,Turner, Ian
, p. 11781 - 11790 (2007/10/03)
1-Benzyl-2-(ethoxycarbonyllmethylene)-2,3,4,5-tetrahydroimidazole undergoes preferred C-alkylation with halogenonakanes, dihalogenoalkanes and epoxides: subsequent removal of of the ethoxycarbonyl group provides a new route to 2-alkyl-4,5-dihydroimidazoles. 1,3-Dihalogenoalkanes afford imidazo[1,2-a]pyridines via C,N-dialkylation.
Imidazolines in synthesis, I: lithio imidazolines formation and C-alkylation
Anderson,Jones,Saunders
, p. 261 - 264 (2007/10/02)
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