1207-99-4 Usage
Description
3-Chloro-10H-phenothiazine is a chemical compound belonging to the phenothiazine family, characterized by the presence of a chlorine atom at the 3-position and a tricyclic structure. It exhibits a diverse range of applications across various industries due to its unique chemical properties.
Uses
Used in Pharmaceutical Industry:
3-Chloro-10H-phenothiazine is used as an active pharmaceutical ingredient for the development of medications targeting various health conditions. Its chemical structure allows for the modulation of biological processes, making it a valuable component in drug formulations.
Used in Dye Industry:
In the dye industry, 3-chloro-10H-phenothiazine is utilized as a colorant, providing vibrant hues and stable coloration in various applications. Its chemical properties contribute to its compatibility with different substrates and resistance to fading.
Used in Lubricant Additives:
3-Chloro-10H-phenothiazine serves as an additive in lubricants, enhancing their performance by improving viscosity, reducing friction, and providing corrosion resistance. Its incorporation into lubricant formulations results in better protection and longevity of machinery and equipment.
Used in Polymer Additives:
In the polymer industry, 3-chloro-10H-phenothiazine is used as an additive to modify the properties of polymers. It can improve characteristics such as stability, color, and resistance to environmental factors, leading to enhanced performance and durability of polymer-based products.
Check Digit Verification of cas no
The CAS Registry Mumber 1207-99-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,2,0 and 7 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1207-99:
(6*1)+(5*2)+(4*0)+(3*7)+(2*9)+(1*9)=64
64 % 10 = 4
So 1207-99-4 is a valid CAS Registry Number.
InChI:InChI=1/C12H8ClNS/c13-8-5-6-10-12(7-8)15-11-4-2-1-3-9(11)14-10/h1-7,14H
1207-99-4Relevant articles and documents
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Cadogan,J.I.G. et al.
, p. 736 (1968)
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Potassium carbonate-mediated tandem C-S and C-N coupling reaction for the synthesis of phenothiazines under transition-metal-free and ligand-free conditions
Wu, San,Hu, Wei-Ye,Zhang, Song-Lin
, p. 24257 - 24260 (2016)
An efficient potassium carbonate-mediated tandem C-S and C-N coupling reaction between N-(2-iodophenyl)acetamides and 2-halo-benzenethiols has been developed. This protocol affords a simple and efficient approach for the construction of phenothiazine derivatives without the need for addition of transition-metal catalyst or ligand for the first time. Furthermore, the reaction can be easily performed on a large scale.
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Shine,H.J. et al.
, p. 2691 - 2697 (1972)
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Cadogan
, p. 11,15 (1969)
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A catalyst system, copper/ N -methoxy-1 H -pyrrole-2-carboxamide, for the synthesis of phenothiazines in poly(ethylene glycol)
Huang, Manna,Hou, Jianying,Yang, Ruiqiao,Zhang, Liting,Zhu, Xinhai,Wan, Yiqian
supporting information, p. 3356 - 3364 (2015/02/02)
A copper/N-methoxy-1H-pyrrole-2-carboxamide catalyst system has been established for the preparation of phenothiazines in good yields by two routes, starting from 2-iodoanilines and 2-bromobenzenethiol and from aryl ortho-dihalides and o-aminobenzenethiols, by conducting the reaction at 90 °C in poly(ethylene glycol)-100 (PEG-100). In addition, the catalyst system was useful for promoting direct arylation of various aryl amines, aliphatic amines, and aqueous ammonia. The simple experimental operation, low loading of catalyst system together with the use of green solvent, makes it attractive for the versatile syntheses of phenothiazines and various amines.
