37750-29-1

Basic information

• Product Name: 2-AMINO-4'-CHLORODIPHENYL SULFIDE
• Synonyms: BENZENAMINE, 2-[(4-CHLOROPHENYL)THIO]-;2-AMINOPHENYL 4-CHLOROPHENYL SULFIDE SOLUTION;2-AMINO-4'-CHLORODIPHENYL SULFIDE;2-(4-CHLOROPHENYLTHIO)ANILINE;TIMTEC-BB SBB003248;2-AMINOPHENYL 4-CHLOROPHENYL SULFIDE SOL ~50% IN TOLUOL;2-amino-4'-chloro;2-(4-chlorophenylthio)aniline solution
• CAS NO: 37750-29-1
• Molecular Formula: C₁₂H₁₀ClNS
• Molecular Weight: 235.73
• Mol File: 37750-29-1.mol
• Article Data: 11

Chemical Properties

• Melting Point: 32 °C(Solv: ethanol (64-17-5); water (7732-18-5))
• Boiling Point: 371.586 °C at 760 mmHg
• Flash Point: 6 °C
• Appearance: /
• Density: 1.317 g/cm³
• Vapor Pressure: 1.02E-05mmHg at 25°C
• Refractive Index: n20/D 1.574
• PKA: 2.87±0.10(Predicted)
• CAS DataBase Reference: 2-AMINO-4'-CHLORODIPHENYL SULFIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-4'-CHLORODIPHENYL SULFIDE(37750-29-1)
• EPA Substance Registry System: 2-AMINO-4'-CHLORODIPHENYL SULFIDE(37750-29-1)

Safety Data

• Hazard Codes: F,Xn
• Statements: 11-20-36/37/38
• Safety Statements: 16-25-26-29-33-36
• RIDADR: UN 1993 3/PG 2
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 37750-29-1(Hazardous Substances Data)

Usage

General Description

2-Amino-4'-chlorodiphenyl sulfide is a chemical compound with the molecular formula C12H10ClNS. It is a sulfide derivative of diphenyl and contains an amino group and a chlorine atom attached to the phenyl rings. 2-AMINO-4'-CHLORODIPHENYL SULFIDE is used as an intermediate in the synthesis of pharmaceuticals, dyes, and agrochemicals. It has also been studied for its potential use in organic electronic devices and materials. The chemical properties and reactivity of 2-Amino-4'-chlorodiphenyl sulfide make it a valuable building block in organic synthesis, contributing to the development of various important products in the pharmaceutical and chemical industries.

InChI:InChI=1/C12H10ClNS/c13-9-5-7-10(8-6-9)15-12-4-2-1-3-11(12)14/h1-8H,14H2

Upstream product

• 6764-10-9 4-chlorophenyl 2-nitrophenyl sulfide 
• 637-87-6 1-Chloro-4-iodobenzene 
• 137-07-5 2-amino-benzenethiol 
• 615-43-0 2-iodophenylamine 
• 106-54-7 p-Chlorothiophenol 
• 615-36-1 2-bromoaniline 
• 95-16-9 1,3-Benzothiazole 
• 62-53-3 aniline 

Downstream Products

• 108975-28-6 N'-[2-(4-chloro-phenylsulfanyl)-phenyl]-N,N-dimethyl-propanediyldiamine 
• 101096-33-7 3-chloro-propionic acid-[2-(4-chloro-phenylsulfanyl)-anilide] 
• 25697-38-5 2-chlorodibenzo-1,4-thiazepin-11(10H)-thione 
• 37930-78-2 2-(4-Chlorphenylthio)-trifluormethansulfonanilid 
• 77711-81-0 2-Chloro-N-[2-(4-chloro-phenylsulfanyl)-phenyl]-acetamide 
• 30213-99-1 1-azido-2-(4-chloro-phenylsulfanyl)-benzene 
• 3159-03-3 2'-Isocyanato-4-chlor-diphenylsulfid 
• 102554-25-6 3-piperidino-propionic acid-[2-(4-chloro-phenylsulfanyl)-anilide] 
• 124136-09-0 9-pyrrolidino-nonanoic acid-[2-(4-chloro-phenylsulfanyl)-anilide] 
• 103649-57-6 2-(4-chloro-phenylsulfanyl)-N-(3-pyrrolidino-propyl)-aniline; dihydrochloride 
• 1207-99-4 3-chloro-10H-phenothiazine 
• 2058-52-8 clothiapine 

Relevant articles and documents

Transition-Metal-Free Synthesis of N-Arylphenothiazines through an N- And S-Arylation Sequence

An efficient synthetic method of N-arylphenothiazines from o-sulfanylanilines under transition-metal-free conditions is disclosed. An N- and S-arylation sequence of o-sulfanylanilines enabled us to synthesize a wide variety of N-arylphenothiazines. In par

Iron-catalyzed S-arylation of benzothiazole with aryl iodides under aqueous medium: Facile synthesis of aryl(2-aminoaryl) sulfides

A simple route for facile access of aryl(2-aminoaryl) sulfide was reported. With the aid of iron(III) chloride catalyst and diamine ligand, benzothiazole was efficiently S-arylated with various aryl iodides (19 examples) in water under air atmosphere. This operationally simple protocol provides aryl(2-aminoaryl) sulfides in moderate to good yields.

Efficient C-S cross-coupling of thiols with aryl iodides catalyzed by Cu(OAc)2·H2O and 2,2′-biimidazole

The classical Ullmann C-S cross coupling reaction of aryl iodides with aromatic/alkyl thiols under catalysis of 15 mol% Cu(OAc)2· H2O and 15 mol% 2,2′-biimidazole works at 80°C in DMSO for 3 h to provide a variety of aryl sulfides in good to excellent yields. The classical Ullmann C-S cross coupling reaction of aryl iodides with aromatic/alkyl thiols under catalysis of 15 mol% Cu(OAc)2· H2O and 15 mol% 2,2′-biimidazole works at 80°C in DMSO for 3 h to provide a variety of aryl sulfides in good to excellent yields. Copyright