1207958-19-7

Basic information

• Product Name: C₁₂H₁₅NO
• Synonyms: C₁₂H₁₅NO
• CAS NO: 1207958-19-7
• Molecular Weight: 189.257
• Mol File: 1207958-19-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₁₂H₁₅NO(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₂H₁₅NO(1207958-19-7)
• EPA Substance Registry System: C₁₂H₁₅NO(1207958-19-7)

Safety Data

• Hazardous Substances Data: 1207958-19-7(Hazardous Substances Data)

Upstream product

• 766-47-2 1-ethynyl-2-methylbenzene 
• 68-12-2 N,N-dimethyl-formamide 
• 2680-03-7 N,N-Dimethylacrylamide 
• 52457-01-9 3-Methylcyclohexa-1,4-diene-3-carboxylic acid 

Relevant articles and documents

Synthesis of Highly Substituted Arenes via Cyclohexadiene-Alkene C-H Cross Coupling and Aromatization

The development of a cross-coupling method for the regioselective β-alkenylation of 2,5-cyclohexadiene carboxylic acid derivatives to form ortho-alkenylarenes through in situ decarboxylation and aromatization is described. The carboxylic acid functionality is used as a traceless directing group for efficient and mild β-alkenylation. The modular sequence comprises a reductive Birch α-alkylation, ionic ?-alkylation followed by a Pd-catalyzed decarboxylative β-alkenylation with subsequent aromatization resulting in an overall three-fold ipso-para-ortho functionalization of readily accessed benzoic acid derivatives. Efficient synthesis of various alkyl-alkenylarenes under mild conditions in moderate to excellent yields is presented.