121440-78-6Relevant articles and documents
Ferrocenyl-QUINAP: A planar chiral P,N-ligand for palladium-catalyzed allylic substitution reactions
Kloetzing, Ralf J.,Knochel, Paul
, p. 116 - 123 (2006)
The new planar chiral P,N-ligands 1a and 1b were prepared via a straightforward enantioselective synthesis using a Negishi cross-coupling and a sulfoxide/lithium exchange. Ligand 1a was successfully applied to Pd-catalyzed allylic alkylation (86% ee) and
Catalytic Asymmetric Allylic Amination with Isatins, Sulfonamides, Imides, Amines, and N-Heterocycles
Balaraman, Kaluvu,Lynch, Ciarán C.,Wolf, Christian
supporting information, p. 3180 - 3184 (2020/04/21)
A generally useful palladium-catalyzed method for the asymmetric allylic amination with a large variety of isatins, sulfonamides, imides, amines, and N-heterocycles is introduced. A single protocol with a readily available catalyst accomplishes this reaction at room temperature with high yields and enantioselectivities often exceeding 90%, which is demonstrated with 31 examples.
Chiral Bronsted acid catalyzed enantioselective intermolecular allylic aminations
Zhuang, Minyang,Du, Haifeng
, p. 4590 - 4593 (2014/06/24)
This paper describes an enantioselective intermolecular allylic amination catalyzed by a chiral Bronsted acid via a possible chiral contact ion pair intermediate. A variety of symmetrical or unsymmetrical allylic alcohols can be smoothly aminated to affor
Palladium/sulfoxide-phosphine-catalyzed highly enantioselective allylic etherification and amination
Feng, Bin,Cheng, Hong-Gang,Chen, Jia-Rong,Deng, Qiao-Hui,Lu, Liang-Qiu,Xiao, Wen-Jing
supporting information, p. 9550 - 9553 (2014/08/18)
The Pd/sulfoxide-phosphine-catalyzed highly enantioselective allylic etherification and amination with a wide range of O- and N-nucleophiles have been developed (up to 97% yield, 98.5% ee). The products can also be conveniently transformed into biologically active chiral heterocycles. This journal is the Partner Organisations 2014.
