1214900-59-0

Basic information

• Product Name: 1-(4-bromo-2-fluorophenyl)propan-1-ol
• Synonyms: 1-(4-bromo-2-fluorophenyl)propan-1-ol
• CAS NO: 1214900-59-0
• Molecular Weight: 233.08
• Mol File: 1214900-59-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-(4-bromo-2-fluorophenyl)propan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-bromo-2-fluorophenyl)propan-1-ol(1214900-59-0)
• EPA Substance Registry System: 1-(4-bromo-2-fluorophenyl)propan-1-ol(1214900-59-0)

Safety Data

• Hazardous Substances Data: 1214900-59-0(Hazardous Substances Data)

Upstream product

• 10467-10-4 ethylmagnesium iodide 
• 57848-46-1 4-bromo-2-fluorobenzaldehyde 
• 925-90-6 ethylmagnesium bromide 

Downstream Products

• 259750-61-3 1-(4-bromo-2-fluorophenyl)propan-1-one 
• 1300582-48-2 tert-butyl 6-bromo-3-ethyl-1H-indazole-1-carboxylate 
• 1300585-17-4 2-(1-(4-amino-3-(3-ethyl-1H-indazol-6-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)-3-(3-fluorophenyl)-4H-chromen-4-one 
• 199172-01-5 6-bromo-3-ethyl-1H-indazole 

Relevant articles and documents

Discovery, Structure-Activity Relationship, and Biological Characterization of a Novel Series of 6-((1 H-Pyrazolo[4,3- b]pyridin-3-yl)amino)-benzo[ d]isothiazole-3-carboxamides as Positive Allosteric Modulators of the Metabotropic Glutamate Receptor 4 (mG

This work describes the discovery and characterization of novel 6-(1H-pyrazolo[4,3-b]pyridin-3-yl)amino-benzo[d]isothiazole-3-carboxamides as mGlu4 PAMs. This scaffold provides improved metabolic clearance and CYP1A2 profiles compared to previo

RING-FUSED COMPOUND

The present invention relates to a compound that has URAT1 inhibitory action, and a URAT1 inhibitor, a blood uric acid level-reducing agent and a pharmaceutical composition comprising the compound. More specifically, the present invention relates to a compound represented by Formula (I) below. [in the formula, R1 is -Q1-A1 and the like; ---- is a double bond or a single bond; when ---- is a double bond, W1 is a nitrogen atom or a group represented by the general formula: =C(Ra)-, and W2 is a nitrogen atom or a group represented by the general formula: =C(Rb) -; when ---- is a single bond, W1 is a group represented by the general formula: -C(Raa)(Rab)- or a group represented by the general formula: -(C=O) -, and W2 is a group represented by the general formula: C(Rba)(Rbb)-, a group represented by the general formula: - (C=O) - or a group represented by the general formula: -N(Rbc)-; W3, W4 and W5 are each independently a nitrogen atom or a methine group and the like that may have a substituent; X is a single bond, an oxygen atom and the like; Y is a single bond or (CRYiRYi')n; and Z is a hydroxyl group or COOR2 and the like.