121496-16-0Relevant articles and documents
HPK1 INHIBITORS, PREPARATION METHOD AND APPLICATION THEREOF
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Page/Page column 178, (2019/11/12)
Disclosed are HPK-1 inhibitors having a structure represented by Formula (X), pharmaceutical compositions comprising the HPK-1 inhibitors, methods of using the HPK-1 inhibitors, such as treating cancers, methods of preparing the HPK-1 inhibitors, and the synthetic intermediates.
Solvent-free copper-catalyzed N-arylation of amino alcohols and diamines with aryl halides
Yin, Huiqing,Jin, Ming,Chen, Wei,Chen, Chen,Zheng, Likang,Wei, Ping,Han, Shiqing
supporting information; experimental part, p. 1265 - 1270 (2012/03/27)
A simple and mild method for the coupling of aryl halides with amino alcohols and diamines is described. The reactions can be performed under ligand-free and solvent-free conditions, and generate the products in good yield.
