591-18-4 Usage
Description
1-Bromo-3-iodobenzene is an organic compound that belongs to the class of halogenated aromatic hydrocarbons. It is characterized by the presence of both bromine and iodine atoms attached to a benzene ring. 1-Bromo-3-iodobenzene is a clear, colorless to light yellow liquid and is sensitive to light. It is also incompatible with strong oxidizing agents, strong bases, and strong acids, necessitating proper storage conditions in a cool place.
Uses
1. Used in Organic Synthesis:
1-Bromo-3-iodobenzene is utilized as a key intermediate in the preparation of various complex organic molecules. Its unique structure allows for specific reactions that can lead to the formation of a range of compounds with diverse applications.
Used in Pharmaceutical Industry:
1-Bromo-3-iodobenzene is used as a building block for the synthesis of certain pharmaceutical compounds. Its halogenated nature enables it to participate in various chemical reactions, making it a valuable component in the development of new drugs.
Used in Chemical Research:
In the field of chemical research, 1-Bromo-3-iodobenzene serves as a model compound for studying the effects of halogen substitution on the properties and reactivity of aromatic systems. It can be used to investigate the influence of bromine and iodine atoms on the electronic and steric properties of benzene, providing insights into the design of new molecules with specific characteristics.
Used in Material Science:
1-Bromo-3-iodobenzene can be employed in the development of novel materials with tailored properties. Its ability to undergo various chemical reactions allows for the creation of new polymers, coatings, and other materials with specific characteristics, such as improved stability, enhanced thermal properties, or unique optical properties.
Check Digit Verification of cas no
The CAS Registry Mumber 591-18-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,9 and 1 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 591-18:
(5*5)+(4*9)+(3*1)+(2*1)+(1*8)=74
74 % 10 = 4
So 591-18-4 is a valid CAS Registry Number.
InChI:InChI=1/C6H4BrI/c7-5-2-1-3-6(8)4-5/h1-4H
591-18-4Relevant articles and documents
Metathesis-active ligands enable a catalytic functional group metathesis between aroyl chlorides and aryl iodides
Lee, Yong Ho,Morandi, Bill
, p. 1016 - 1022 (2018/09/06)
Current methods for functional group interconversion have, for the most part, relied on relatively strong driving forces which often require highly reactive reagents to generate irreversibly a desired product in high yield and selectivity. These approaches generally prevent the use of the same catalytic strategy to perform the reverse reaction. Here we describe a catalytic functional group metathesis approach to interconvert, under CO-free conditions, two synthetically important classes of electrophiles that are often employed in the preparation of pharmaceuticals and agrochemicals—aroyl chlorides (ArCOCl) and aryl iodides (ArI). Our reaction design relies on the implementation of a key reversible ligand C–P bond cleavage event, which enables a non-innocent, metathesis-active phosphine ligand to mediate a rapid aryl group transfer between the two different electrophiles. Beyond enabling a practical and safer approach to the interconversion of ArCOCl and ArI, this type of ligand non-innocence provides a blueprint for the development of a broad range of functional group metathesis reactions employing synthetically relevant aryl electrophiles.
PROCESS FOR THE PREPARATION OF N-IODOAMIDES
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Paragraph 00215-00216, (2015/05/26)
The present invention provides new stable crystalline N-iodoamides - 1-iodo- 3,5,5-trimethylhydantoin (1-ITMH) and 3-iodo-4,4-dimethyl-2-oxazolidinone (IDMO). The present invention further provides a process for the preparation of organic iodides using N-iodoamides of this invention and recovery of the amide co-products from waste water.
PROCESS FOR THE PREPARATION OF IODIDES
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Page/Page column 34, (2012/01/05)
This invention is directed to a process for the preparation of high yield alkyl or aryl iodide from its corresponding carboxylic acid using N-iodo amides.