1219940-12-1

Basic information

• Product Name: 1-(4-Chlorophenyl)ethylidene(methoxy)amine
• Synonyms: 1-(4-Chlorophenyl)ethylidene(methoxy)amine;1-(4-Chlorophenyl)ethanone O-Methyl oxiMe
• CAS NO: 1219940-12-1
• Molecular Formula: C₉H₁₀ClNO
• Molecular Weight: 183.6348
• Mol File: 1219940-12-1.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(4-Chlorophenyl)ethylidene(methoxy)amine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-Chlorophenyl)ethylidene(methoxy)amine(1219940-12-1)
• EPA Substance Registry System: 1-(4-Chlorophenyl)ethylidene(methoxy)amine(1219940-12-1)

Safety Data

• Hazardous Substances Data: 1219940-12-1(Hazardous Substances Data)

Usage

Description

1-(4-Chlorophenyl)ethylidene(methoxy)amine, also known as 4-chloroamphetamine, is a chemical compound with a molecular formula C10H12ClNO. It is an amphetamine derivative featuring a methoxy group attached to the ethylidene moiety. 1-(4-Chlorophenyl)ethylidene(methoxy)amine acts as a stimulant that impacts the central nervous system and has been investigated for its potential psychoactive effects. Classified as a substituted amphetamine, it shares characteristics with other amphetamine derivatives such as MDMA and methamphetamine.

Uses

Used in Pharmaceutical Research:
1-(4-Chlorophenyl)ethylidene(methoxy)amine is used as a research chemical for studying its interactions with neurotransmitter systems and potential therapeutic applications. Its psychoactive properties and effects on the central nervous system make it a subject of interest for understanding its mechanisms of action and possible uses in medicine.
Used in Psychopharmacology:
In the field of psychopharmacology, 1-(4-Chlorophenyl)ethylidene(methoxy)amine is used as a compound to explore its potential effects on mood, cognition, and behavior. This can contribute to the development of new treatments for various psychiatric and neurological disorders.
Used in Forensic Toxicology:
1-(4-Chlorophenyl)ethylidene(methoxy)amine is also used in forensic toxicology for the identification and analysis of substances related to cases involving substance abuse or poisoning. Its classification as a substituted amphetamine makes it relevant for understanding the effects of similar compounds on human health.
Please note that due to the compound's abuse potential and recreational use, it is essential to handle and study this compound with strict regulatory oversight and ethical considerations.

Upstream product

• 593-56-6 N-methoxylamine hydrochloride 
• 99-91-2 para-chloroacetophenone 

Downstream Products

• 1219939-85-1 3-chloro-9-di(m-tolyl)methylene-6-methyl-9H-fluorene 
• 1219939-82-8 6-chloro-2-methyl-9,10-di(p-tolyl)phenanthrene 
• 1219939-95-3 diethyl 4,4'-((6-chloro-7-(ethoxycarbonyl)-9H-fluoren-9-ylidene)methylene)dibenzoate 
• 1380197-95-4 6-chloro-1,4-dimethyl-3-phenylisoquinoline 
• 1417412-29-3 (5-chloro-2-(1-(methoxyimino)ethyl)phenyl)(phenyl)methanone 
• 1448171-21-8 C₁₄H₁₉ClN₂O 
• 1447826-90-5 5-chloro-2-(1-(methoxyimino)ethyl)benzonitrile 
• 1510826-79-5 (5-chloro-2-(1-(methoxyimino)ethyl)phenyl )( 4-methoxyphenyl)methanone 
• 1510826-82-0 (5-chloro-2-(1-(methoxyimino)ethyl)phenyl)(4-(trifluoromethyl)phenyl)methanone 
• 1510826-85-3 (5-chloro-2-(1-(methoxyimino)ethyl)phenyl)(4-fluorophenyl)methanone 
• 1510826-88-6 (4-bromophenyl)(5-chloro-2-(1-(methoxyimino)ethyl)phenyl)methanone 
• 1510826-91-1 (5-chloro-2-(1-(methoxyimino)ethyl)phenyl)(m-tolyl)methanone 
• 1510826-94-4 (5-chloro-2-(1-(methoxyimino)ethyl)phenyl)(o-tolyl)methanone 
• 1510826-97-7 (5-chloro-2-(1-(methoxyimino)ethyl)phenyl)(2-chlorophenyl)methanone 

Relevant articles and documents

Access to Branched Allylarenes via Rhodium(III)-Catalyzed C-H Allylation of (Hetero)arenes with 2-Methylidenetrimethylene Carbonate

A rhodium(III)-catalyzed C-H allylation of (hetero)arenes by using 2-methylidenetrimethylene carbonate as an efficient allylic source has been developed for the first time. Five different directing groups including oxime, N-nitroso, purine, pyridine, and pyrimidine were compatible, delivering various branched allylarenes bearing an allylic hydroxyl group in moderate to excellent yields.

Reusable Palladium Nanoparticles Catalyzed Oxime Ether Directed Mono Ortho-Hydroxylation under Phosphine Free Neutral Condition

An efficient, reusable and stable binaphthyl stabilized Pd-nanoparticles (Pd-BNP) catalyzed the direct ortho-C?H hydroxylation of acetophenone oxime ethers under neutral and phosphine ligand-free condition has been developed. A readily available, economic, safe and greener oxidant oxone has been used in this direct ortho-hydroxylation. The scope of the reaction has been studied with various acetophenone oxime ethers including electron rich to electron deficient system and the reaction afforded only mono hydroxylated products in a highly regioselective manner. Several control experiment results confirmed that the oxone is the hydroxyl source. The Pd-BNP catalyst has been reused up to five times. The heterogeneous test confirmed that the reaction is catalyzed by the heterogeneous Pd-BNP catalyst. (Figure presented.).

Palladium-Catalyzed C(sp2)-H Acetoxylation via Electrochemical Oxidation

Palladium-catalyzed arene C(sp2)-H acetoxylation has emerged as a powerful tool to construct a carbon-oxygen (C-O) bond. However, the requirement of stoichiometric chemical oxidants for this transformation possesses a significant disadvantage.