1222078-43-4

Basic information

• Product Name: 3'-O-(2-azidomethlbenzoyl)-2'-O-TBDMS-N-Bz-adenosine
• Synonyms: 3'-O-(2-azidomethlbenzoyl)-2'-O-TBDMS-N-Bz-adenosine
• CAS NO: 1222078-43-4
• Molecular Weight: 644.762
• Mol File: 1222078-43-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3'-O-(2-azidomethlbenzoyl)-2'-O-TBDMS-N-Bz-adenosine(CAS DataBase Reference)
• NIST Chemistry Reference: 3'-O-(2-azidomethlbenzoyl)-2'-O-TBDMS-N-Bz-adenosine(1222078-43-4)
• EPA Substance Registry System: 3'-O-(2-azidomethlbenzoyl)-2'-O-TBDMS-N-Bz-adenosine(1222078-43-4)

Safety Data

• Hazardous Substances Data: 1222078-43-4(Hazardous Substances Data)

Upstream product

• 289712-58-9 2-(azidomethyl)benzoyl chloride 
• 1222078-42-3 C₅₂H₅₄N₈O₈Si 
• 289712-57-8 2-(azidomethyl)benzoic acid 
• 329781-57-9 methyl 2-(azidomethyl) benzoate 
• 89-71-4 2-Methyl-benzoic acid methyl ester 
• 2417-73-4 methyl 2-bromomethylbenzoate 
• 933-88-0 ortho-toluoyl chloride 
• 118-90-1 ortho-methylbenzoic acid 

Downstream Products

• 1222078-46-7 DMTr[AA]AZMB 

Relevant articles and documents

Chemical synthesis of bioactive siRNA in solution phase by using 2-(azidomethyl)benzoyl as 3′-hydroxyl group protecting group

A protecting group AZMB was introduced to ribonucleosides 3′-hydroxyl group to facilitate solution phase synthesis of siRNA. The protection and cleavage reaction were carried out in mild conditions, that is protection by acyl chloride and cleavage by triphenylphosphine. The synthesized siRNA showed good biological activity to suppress targeted superoxide dismutase gene expression.