1224567-99-0

Basic information

• Product Name: 3-{[(1R)-1-(naphthalen-1-yl)ethyl]amino}-1-[3-(trifluoromethyl)phenyl]propan-1-one hydrochloride
• Synonyms: 3-{[(1R)-1-(naphthalen-1-yl)ethyl]amino}-1-[3-(trifluoromethyl)phenyl]propan-1-one hydrochloride
• CAS NO: 1224567-99-0
• Molecular Weight: 407.863
• Mol File: 1224567-99-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-{[(1R)-1-(naphthalen-1-yl)ethyl]amino}-1-[3-(trifluoromethyl)phenyl]propan-1-one hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 3-{[(1R)-1-(naphthalen-1-yl)ethyl]amino}-1-[3-(trifluoromethyl)phenyl]propan-1-one hydrochloride(1224567-99-0)
• EPA Substance Registry System: 3-{[(1R)-1-(naphthalen-1-yl)ethyl]amino}-1-[3-(trifluoromethyl)phenyl]propan-1-one hydrochloride(1224567-99-0)

Safety Data

• Hazardous Substances Data: 1224567-99-0(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 82572-04-1 (R)-<1-(1-Naphthyl)ethyl>ammonium chloride 
• 349-76-8 3'-(trifluoromethyl)acetophenone 
• 1224568-01-7 N,N,N-trimethyl-3-oxo-3-(3-(trifluoromethyl)phenyl)propan-1-ammonium iodide 
• 3886-70-2 (R)-1-(1-Naphthyl)ethylamine 

Downstream Products

• 226256-56-0 cinacalcet 
• 955373-56-5 (2E)-N-[(1R)-1-(1-naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]prop-2-en-1-amine 
• 1224568-02-8 (R)-3-(1-(naphthalen-1-yl)ethylamino)-1-(3-(trifluoromethyl)phenyl)propan-1-ol 
• 1273259-52-1 (R)-3-chloro-N-(1-(naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine hydrochloride 
• 1273259-50-9 (R)-3-(1-(naphthalen-1-yl)ethylamino)-1-(3-(trifluoromethyl)phenyl)propan-1-ol hydrochloride 
• 364782-34-3 cinacalcet hydrochloride 
• 1240705-75-2 3-((R)-1-(naphthalen-1-yl)ethylammonio)-1-(3-trifluoromethylphenyl)propyl sulfate 

Relevant articles and documents

PROCESS FOR PREPARING CINACALCET

A process for preparing N-[(1R)-1-(1-naphthyl)ethyl]-3-[3-(trifluoromethyl)-phenyl]propan-1-amine of formula hydrochloride salt of formula (I); i.e. Cinacalcet.HC1 and its intermediate of formula (IX).

PROCESS FOR PREPARING CINACALCET HYDROCHLORIDE

A process for preparing N-[(1lR)-1-(1-naphthyl)ethyl]-3-[3-(trifluoromethyl)- phenyl]propan-1-amine hydrochloride salt of formula (I) i.e. Cinacalcet hydrochloride and its intermediates of formulae (VII) and (VIII) wherein Z is chloride or another pharmaceutically acceptable anionic counterion.