1231930-57-6

Basic information

• Product Name: 5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)-N-(5-(piperazin-1-ylmethyl)pyridin-2-yl)pyrimidin-2-amine
• Synonyms: 5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)-N-(5-(piperazin-1-ylmethyl)pyridin-2-yl)pyrimidin-2-amine
• CAS NO: 1231930-57-6
• Molecular Weight: 478.548
• Mol File: 1231930-57-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)-N-(5-(piperazin-1-ylmethyl)pyridin-2-yl)pyrimidin-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)-N-(5-(piperazin-1-ylmethyl)pyridin-2-yl)pyrimidin-2-amine(1231930-57-6)
• EPA Substance Registry System: 5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)-N-(5-(piperazin-1-ylmethyl)pyridin-2-yl)pyrimidin-2-amine(1231930-57-6)

Safety Data

• Hazardous Substances Data: 1231930-57-6(Hazardous Substances Data)

Upstream product

• 1178566-52-3 4-((6-aminopyridin-3-yl)methyl)piperazine-1-carbamic acid tert-butyl ester 
• 69879-22-7 6-amino-3-pyridinecarbaldehyde 
• 1231930-48-5 tert-butyl 4-((6-((5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-yl)amino)pyridin-3-yl)methyl)piperazine-1-carboxylate 

Relevant articles and documents

Pyrimidine derivative as well as preparation method and application thereof

Embodiments of the invention relate to a pyrimidine derivative as well as a preparation method and application thereof. The pyrimidine derivative is selected from a compound as shown in a general formula (I) or a tautomer, an enantiomer, a diastereoisomer, a meracemate or a raceme of the compound, or a mixture of tautomer, the enantiomer, the diastereoisomer, the meracemate or the raceme, or a pharmaceutically acceptable salt or a prodrug of the compound. The pyrimidine derivative shows an excellent CDK inhibition effect and action.