1233324-80-5

Basic information

• Product Name: 5-(aminomethyl)-3-(trifluoromethyl)aniline
• Synonyms: 5-(aminomethyl)-3-(trifluoromethyl)aniline
• CAS NO: 1233324-80-5
• Molecular Weight: 190.168
• Mol File: 1233324-80-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-(aminomethyl)-3-(trifluoromethyl)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(aminomethyl)-3-(trifluoromethyl)aniline(1233324-80-5)
• EPA Substance Registry System: 5-(aminomethyl)-3-(trifluoromethyl)aniline(1233324-80-5)

Safety Data

• Hazardous Substances Data: 1233324-80-5(Hazardous Substances Data)

Upstream product

• 20566-80-7 3-nitro-5-(trifluoromethyl)benzonitrile 
• 49674-28-4 3-amino-5-(trifluoromethyl)benzonitrile 

Downstream Products

• 693249-72-8 tert-butyl [4-amino-2-(trifluoromethyl)benzyl]carbamate 
• 942072-08-4 ((R)-N-[3-(aminomethyl)-5-(trifluoromethyl)phenyl]-7-(2-[(cyclopropylcarbonyl)amino]pyridin-4-yl)oxy)-1,2,3,4-tetrahydronaphthalene-2-carboxamide 
• 942073-62-3 ((S)-N-[3-(aminomethyl)-5-(trifluoromethyl)phenyl]-7-(2-[(cyclopropylcarbonyl)amino]pyridin-4-yl)oxy)-1,2,3,4-tetrahydronaphthalene-2-carboxamide 

Relevant articles and documents

CHEMICAL COMPOUNDS

The invention is directed to substituted heteroaryl derivatives. Specifically, the invention is directed to compounds according to Formula Q: wherein D, L, M, W, X, Y, and Z are defined herein. The compounds of the invention are inhibitors of DNA methyltransferase (DNMT) activity - including DNMT1, DNMT3a, or DNMT3b- and are useful in the treatment of cancer and hyperproliferative diseases. Accordingly, the invention is further directed to pharmaceutical compositions comprising a compound of the invention. The invention is still further directed to methods of inhibiting DNMT activity and treatment of disorders associated therewith using a compound of the invention or a pharmaceutical composition comprising a compound of the invention