123522-71-4Relevant articles and documents
2(3H)-and 2(5H)-furanones. VII. Chirality transfer on the tetronic acid templates
Momose, Takefumi,Toyooka, Naoki,Nishio, Morihiro,Shinoda, Hiroyuki,Fujii, Hiromi,Yanagino, Hironobu
, p. 1321 - 1343 (2007/10/03)
The chirality transfer on the β-tetronic acid templates has been examined via highly diastereoselective alkylation or the Michael reaction at the α-position of the acids. Synthetic utility of this transfer procedure was demonstrated by the formal synthesis of (+)-cassiol and enantiodivergent synthesis of O-methyljoubertiamine.
FIRST TOTAL SYNTHESIS OF (+)-CASSIOL. A POTENT ANTIULCEROGENIC COMPOUND
Takemoto, Tadahiro,Fukaya, Chikara,Yokoyama, Kazumasa
, p. 723 - 724 (2007/10/02)
The first total synthesis of (S)-(+)-Cassiol (2) is described.
