123884-08-2

Basic information

• Product Name: 3'-deoxy-5'-O-(phenoxythiocarbonyl)thymidine
• Synonyms: 3'-deoxy-5'-O-(phenoxythiocarbonyl)thymidine
• CAS NO: 123884-08-2
• Molecular Weight: 362.406
• Mol File: 123884-08-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3'-deoxy-5'-O-(phenoxythiocarbonyl)thymidine(CAS DataBase Reference)
• NIST Chemistry Reference: 3'-deoxy-5'-O-(phenoxythiocarbonyl)thymidine(123884-08-2)
• EPA Substance Registry System: 3'-deoxy-5'-O-(phenoxythiocarbonyl)thymidine(123884-08-2)

Safety Data

• Hazardous Substances Data: 123884-08-2(Hazardous Substances Data)

Upstream product

• 50-89-5 thymidine 
• 1005-56-7 phenylcarbonochloridothioate 
• 123884-07-1 3',5'-bis-O-(phenoxythiocarbonyl)thymidine 

Downstream Products

• 3416-05-5 3'-Deoxythymidine 

Relevant articles and documents

Facile Synthesis of 3'-O-Methylthymidine and 3'-Deoxythymidine and Related Deoxygenated Thymidine Derivative: A New Method for Selective Deoxygenation of Secondary Hydroxy Groups

This paper deals with convenient synthesis of 3'-O-methylthymidine (2) and 3'-deoxythymidine (3), which involve Ag2O-promoted methylation and Barton-Robins reductive deoxygenation, respectively.New methods for the regioselective 3'- and 5'-deoxygenation of thymidine have also been developed.Namely, compound 3 was synthesized by the 3',5'-O-diacylation of thymidine with phenyl chlorothionoformate (PTCF) followed by the selective 3'-reduction with tributyltin hydride and successive alkaline hydrolysis. 5'-Deoxythymidine (18) was obtained by the 5'-selective acylation of thymidine with PTCF followed by reduction with tributyltin hydride.