124-02-7Relevant articles and documents
Preparation method of diallylamine and hydrochloride thereof
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Paragraph 0047; 0048; 0051; 0052; 0053, (2019/03/08)
The invention belongs to the technical field of organic synthesis, and in particular relates to a preparation method of diallylamine and hydrochloride thereof. The preparation method comprises the following steps: inputting ammonia water into a reaction kettle, adding a catalyst, dropwise adding 3-chloropropene at a constant temperature and a constant pressure, heating the mixture to 50-55 DEG C after dropwise addition, keeping the temperature for 1 hour, and reducing the temperature to 35-40 DEG C to obtain slurry; extracting the slurry to a distilling kettle, adding sodium hydroxide and a byproduct ammonium chloride into the distilling kettle to react, absorbing generated ammonia water with water and reusing the same, neutralizing the same, starting distillation till a water phase is obtained, adding caustic soda flakes to dehydrate, cyclically using the dehydrated alkaline liquor t o obtain a diallylamine coarse product; and inputting the coarse product into a rectifying kettle, taking a small amount of precomponent first, then receiving diallylamine, and returning the precomponent to a reaction kettle to be used. The diallylamine and hydrochloride thereof are prepared by adopting an amination process, so that the method is safe and is guaranteed, and meanwhile, excessive ammonia water and alkaline water are fully recycled, so that the preparation method is low in energy consumption and little in pollution, and the three wastes can be recycled.
O -Phthalaldehyde catalyzed hydrolysis of organophosphinic amides and other P(O)-NH containing compounds
Li, Bin-Jie,Simard, Ryan D.,Beauchemin, André M.
supporting information, p. 8667 - 8670 (2017/08/10)
Over 50 years ago, Jencks and Gilchrist showed that formaldehyde catalyses the hydrolysis of phosphoramidate through electrophilic activation, induced by covalent attachment to its nitrogen atom. Given our interest in the use of aldehydes as catalysts, this work was revisited to identify a superior catalyst, o-phthalaldehyde, which facilitates hydrolyses of various organophosphorus compounds bearing P(O)-NH subunits under mild conditions. Interestingly, chemoselective hydrolysis of the P(O)-N bonds could be accomplished in the presence of P(O)-OR bonds.
GOLD CATALYZED HYDROAMINATION OF ALKYNES AND ALLENES
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Page/Page column 21; 23; 2/13, (2010/01/29)
Methods are provided for the catalytic hydroamination of compounds having an alkyne or allene functional group, in which the compound is contacted with ammonia or an amine in the presence of a catalytic amount of a gold complex under conditions sufficient for hydroamination to occur.