1242288-73-8Relevant articles and documents
Preparation method of 2-arylbenzothiazole compound
-
Paragraph 0014; 0071; 0072; 0073, (2017/03/25)
The invention relates to a preparation method of a 2-arylbenzothiazole compound. The method comprises the steps that a benzothiazole compound, diaryliodonium salt, a catalyst, a phosphine ligand and alkali are added into an organic solvent, reacting is conducted for 20-36 hours at the temperature of 60 DEG C to 100 DEG C, and after complete reacting is achieved, reaction liquid is obtained; after the reaction liquid is sequentially subjected to conventional extraction, drying, concentration and column chromatography separation, the compound is obtained. The preparation method belongs to a two-component one-pot reaction, the conditions are mild, the raw materials are easy to prepare and obtain, operation is easy, the yield is high, green environmental protection and economic conservation are achieved, large-scale production can be achieved, and the good application potential on medicine, pesticides, organic synthesis and materials and the good industrial application prospect are achieved.
