7466-32-2

Basic information

• Product Name: 6-chloro-2-phenyl-1,3-benzothiazole
• CAS NO: 7466-32-2
• Molecular Formula: C₁₃H₈ClNS
• Molecular Weight: 245.7273
• Mol File: 7466-32-2.mol
• Article Data: 42

Chemical Properties

• Boiling Point: 389°C at 760 mmHg
• Flash Point: 189.1°C
• Density: 1.339g/cm³
• Vapor Pressure: 6.58E-06mmHg at 25°C
• Refractive Index: 1.689
• CAS DataBase Reference: 6-chloro-2-phenyl-1,3-benzothiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 6-chloro-2-phenyl-1,3-benzothiazole(7466-32-2)
• EPA Substance Registry System: 6-chloro-2-phenyl-1,3-benzothiazole(7466-32-2)

Safety Data

• Hazardous Substances Data: 7466-32-2(Hazardous Substances Data)

Usage

General Description

6-chloro-2-phenyl-1,3-benzothiazole is a chemical compound with the molecular formula C13H8ClNS. It is a member of the benzothiazole family of compounds, which are known for their wide range of applications such as in pharmaceuticals, agrochemicals, and materials science. The presence of a chloro group and a phenyl group in the compound gives it unique chemical properties and potential biological activities. This chemical may be used in the development of new drugs or agrochemicals due to its structural characteristics and potential biological activities. Additionally, it may also have applications in materials science due to its potential for modifying the physical and chemical properties of certain materials.

Upstream product

• 5310-28-1 N-(4-chlorophenyl)thiobenzamide 
• 100-52-7 benzaldehyde 
• 3292-54-4 6-chloro-3H-benzo[d][1,2,3]dithiazole 2-oxide 
• 98-88-4 benzoyl chloride 
• 65-85-0 benzoic acid 
• 3622-23-9 2,6-dichloro-1,3-benzothiazole 
• 98-80-6 phenylboronic acid 
• 23474-98-8 2-amino-5-chlorobenzenethiol 
• 614-16-4 Benzoylacetonitrile 
• 106-47-8 4-chloro-aniline 
• 118063-94-8 2,6-Dichloro-2λ⁴-benzo[1,2,3]dithiazole 
• 35576-53-5 6-Chloro-1,2,3-benzodithiazol-1-ium chloride 
• 2866-82-2 N-(4-chlorophenyl)benzamide 
• 98-86-2 acetophenone 

Downstream Products

• 1379479-34-1 2-([1,1':3',1''-terphenyl]-2'-yl)-6-chlorobenzo[d]thiazole 
• 1379479-35-2 6-chloro-2-(4,4''-dichloro-[1,1':3',1''-terphenyl]-2'-yl)benzo[d]thiazole 
• 1379479-33-0 6-chloro-2-(4,4''-dimethyl-[1,1':3',1''-terphenyl]-2'-yl)benzo[d]thiazole 
• 1242288-73-8 6-chloro-2-(2-fluorophenyl)benzo[d]thiazole 
• 1242286-86-7 6-chloro-2-(2,6-difluorophenyl)benzo[d]thiazole 
• 1242288-47-6 2-(3-nitrophenyl)-6-chlorobenzothiazole 

Relevant articles and documents

A highly regioselective synthesis of 2-aryl-6-chlorobenzothiazoles employing microwave-promoted Suzuki-Miyaura coupling reaction

Suzuki-Miyaura coupling reactions of 2,6-dichlorobenzothiazole with arylboronic acids, promoted by microwave heating, efficiently produce 2-aryl-6-chlorobenzothiazoles in a highly regioselective manner. This process serves as the foundation for a simple m

Graphene oxide-catalyzed synthesis of benzothiazoles with amines and elemental sulfur via oxidative coupling strategy of amines to imines

The graphene oxide-catalyzed coupling and cyclization reactions of primary amines with elemental sulfur was developed to afford various optically property benzothiazoles. This coupling and cyclization strategies proceeded under the oxidant system graphene oxide/O2 and constructed carbon-heteroatom (N, S) bonds with amines and elemental sulfur. Due to benzothiazoles as common chromophores, these products exhibited intriguing fluorescence properties, including outstanding Stokes shifts (up to 161 nm) and quantum yields (up to 74%). Utilizing the products’ unique fluorescence response in different solvents, β-naphthothiazole 4a showed excellent aggregation-induced emission properties in 1,2-dichloroethane, which was 60 times higher than in tetrahydrofuran.

Photocatalyst- And Transition-Metal-Free Visible-Light-Promoted Intramolecular C(sp2)-S Formation

A photocatalyst- and transition-metal-free visible-light-induced cyclization of ortho-halothiobenzanilides has been developed. Upon irradiation with visible light, substrates undergo dehalogenative cyclization to 2-aryl benzothiazoles with high efficiency and selectivity. This photocyclization exhibits a high tolerance to various functional groups, is applicable for the synthesis of 2-alkyl benzothiazoles, and is easy to set up for gram-scale reaction.