1245504-98-6Relevant articles and documents
Preheated fly-ash catalyzed aldol condensation: Efficient synthesis of chalcones and antimicrobial activities of some 3-thienyl chalcones
Arulkumaran, Ranganathan,Vijayakumar, Sambandhamoorthy,Sakthinathan, S. Pazhanivel,Kamalakkannan, Dakshnamoorthy,Ranganathan, Kaliyaperumal,Suresh, Ramamoorthy,Sundararajan, Rajasekaran,Vanangamudi, Ganesan,Thirunarayanan, Ganesamoorthy
, p. 1684 - 1690 (2013/09/24)
In the present study we have prepared a series of some chalcones using solvent - free Aldol - condensation by microwave irradiation. The yields of the ketones are more than 60%. The synthesised chalcones were characterized by their analytical, physical and spectral data. The antimicrobial activities of substituted styryl 3-thienyl ketones have been studied using Bauer-Kirby method.
Unexpected lactonization accompanying addition of ethyl acetoacetate to chalcones derived from 3-acetylthiophene
Budak, Yakup,Findik, Esra
scheme or table, p. 1255 - 1261 (2012/01/03)
Chalcone derivatives containing thiophene ring were prepared by the condensation of 3-acetylthiophene with aromatic aldehydes in excellent yields. The addition of ethyl acetoacetate to chalcone derivatives 3a-3h in the presence of solid NaOH in CH2Cl2 resulted in the formation of the mixture of bicyclic lactone derivatives 5a-5h and 6-(ethoxycarbonyl) cyclohexenone derivatives 6a-6h.