1250907-71-1

Basic information

• Product Name: methyl (E)-4-(4-fluorophenyl)-3-butenoate
• Synonyms: methyl (E)-4-(4-fluorophenyl)-3-butenoate
• CAS NO: 1250907-71-1
• Molecular Weight: 194.206
• Mol File: 1250907-71-1.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: methyl (E)-4-(4-fluorophenyl)-3-butenoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (E)-4-(4-fluorophenyl)-3-butenoate(1250907-71-1)
• EPA Substance Registry System: methyl (E)-4-(4-fluorophenyl)-3-butenoate(1250907-71-1)

Safety Data

• Hazardous Substances Data: 1250907-71-1(Hazardous Substances Data)

Upstream product

• 127404-66-4 (E)-4-(4-fluorophenyl)-3-butenoic acid 
• 74-88-4 methyl iodide 
• 127404-66-4 4-(4-fluorophenyl)but-3-enoic acid 
• 459-57-4 4-fluorobenzaldehyde 
• 67-56-1 methanol 
• 460-00-4 1-Bromo-4-fluorobenzene 
• 1737-16-2 1-allyl-4-fluorobenzene 
• 201230-82-2 carbon monoxide 
• 160874-85-1 2-(4-fluorophenyl)-[1,3,2]-dioxaborolane 
• 3724-55-8 methyl but-3-enoate 

Downstream Products

• 192701-91-0 methyl 5-(4-fluorophenyl)-1H-pyrazole-3-carboxylate 
• 7515-50-6 (E)-4-(4-fluorophenyl)but-3-en-1-ol 

Relevant articles and documents

Intramolecular Cyclization of Vinyldiazoacetates as a Versatile Route to Substituted Pyrazoles

Vinyldiazo compounds undergo a thermal electrocyclization to form pyrazoles in yields of up to 95percent. The reactions are operationally simple, use readily available starting materials, require no intervention of a catalyst, and enable the synthesis of mono-, di- A nd tri-substituted pyrazoles. With the ability to produce highly substituted pyrazoles and the flexibility in installing various types of substituents, this method constitutes a new entry to this valuable heterocyclic scaffold and may be of interest to all branches of the chemical industry.

Synthesis of Allylboranes via Cu(I)-Catalyzed B-H Insertion of Vinyldiazoacetates into Phosphine-Borane Adducts

Cu(I) catalysts enable C-B bond formation via direct insertion of vinyldiazoacetates into B-H bonds of borane-phosphine Lewis adducts to form phosphine-protected allylboranes under mild conditions. The resulting allylborane-phosphine Lewis adducts can be used in the diastereoselective allylation of aldehydes directly without the need for removal of the phosphine. The allylation reaction proceeds with high diastereoselectivity and yields 5,6-disubstituted dihydropyranones after treatment with an appropriate acid.

Highly regioselective palladium-catalysed oxidative allylic C-H carbonylation of alkenes

Pd-catalysed direct oxidative carbonylation of allylic C-H bonds with carbon monoxide was first described. This new procedure shows that the inherent requirement for a leaving group in the Tsuji-Trost palladium-catalysed allylic carbonylation can be lifted, which provides a new route for accessing more synthetically useful β-enoic acid esters with high regioselectivity. The Royal Society of Chemistry 2011.