125311-43-5

Basic information

• Product Name: Pyridine, 2,4-bis(2-phenylethenyl)-, (E,E)-
• CAS NO: 125311-43-5
• Molecular Formula: C21H17N
• Molecular Weight: 283.373
• Mol File: 125311-43-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Pyridine, 2,4-bis(2-phenylethenyl)-, (E,E)-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridine, 2,4-bis(2-phenylethenyl)-, (E,E)-(125311-43-5)
• EPA Substance Registry System: Pyridine, 2,4-bis(2-phenylethenyl)-, (E,E)-(125311-43-5)

Safety Data

• Hazardous Substances Data: 125311-43-5(Hazardous Substances Data)

Upstream product

• 108-47-4 2,4-lutidine 
• 100-46-9 benzylamine 
• 100-52-7 benzaldehyde 
• 58530-53-3 2,4-dibromopyridine 
• 6783-05-7 trans-2-phenylvinylboronic acid 

Downstream Products

• 125311-44-6 (E,E)-2,4-bis(2-phenylethenyl)pyridine-1-oxide 

Relevant articles and documents

Deaminative Olefination of Methyl N-Heteroarenes by an Amine Oxidase Inspired Catalyst

We explored the bioinspired o-quinone cofactor catalyzed aerobic primary amine dehydrogenation for a cascade olefination reaction with nine different methyl N-heteroarenes, including pyrimidines, pyrazines, pyridines, quinolines, quinoxolines, benzimidazoles, benzoxazoles, benzthiazoles, and triazines. An o-quinone catalyst phd (1,10-phenanthroline-5,6-dione) combined with a Br?nsted acid catalyzed the reaction. N-Heteroaryl stilbenoids were synthesized in high yields and (E)-selectivities under mild conditions using oxygen (1 atm) as the sole oxidant without needing transition-metal salt, ligand, stoichiometric base, or oxidant.

Lobelane analogues as novel ligands for the vesicular monoamine transporter-2

A series of lobelane analogues has been synthesized and their structure-activity relationships at the vesicular monoamine transporter-2 (VMAT2) have been evaluated. The most potent analogues in this series were the cis-2,6-piperidino analogues, 25b, 27b, 28b, and 30b, with Ki values ranging from 430 to 580 nM.