1255771-99-3Relevant articles and documents
Enantioselective phase-transfer catalysis: Synthesis of pyrazolines
Make, Olivier,Dez, Isabelle,Levacher, Vincent,Briere, Jean-Francois
supporting information; experimental part, p. 7072 - 7075 (2010/11/05)
All paired up: Under catalytic phase-transfer conditions the formation of a chiral ion pair between quininium cation 1 and hydrazine anion 2 led to an enantioselective aza-Michael cyclocondensation domino reaction to furnish pyrazolines. A convenient one-pot protocol allowed exchange of the functional group (R1) on the nitrogen atom.