16619-28-6

Basic information

• Product Name: 2-Propen-1-one, 3-(2-methylphenyl)-1-phenyl-
• CAS NO: 16619-28-6
• Molecular Formula: C16H14O
• Molecular Weight: 222.287
• Mol File: 16619-28-6.mol
• Article Data: 25

Chemical Properties

• CAS DataBase Reference: 2-Propen-1-one, 3-(2-methylphenyl)-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propen-1-one, 3-(2-methylphenyl)-1-phenyl-(16619-28-6)
• EPA Substance Registry System: 2-Propen-1-one, 3-(2-methylphenyl)-1-phenyl-(16619-28-6)

Safety Data

• Hazardous Substances Data: 16619-28-6(Hazardous Substances Data)

Upstream product

• 89-95-2 2-methyl-benzyl alcohol 
• 98-86-2 acetophenone 
• 52457-01-9 3-Methylcyclohexa-1,4-diene-3-carboxylic acid 
• 768-03-6 Phenyl vinyl ketone 
• 529-20-4 2-methylphenyl aldehyde 

Downstream Products

• 1254200-28-6 (R)-dimethyl 2-(3-oxo-3-phenyl-1-O-tolylpropyl)malonate 
• 1373121-99-3 1-phenyl-3-(phenylthio)-3-o-tolylpropan-1-one 
• 1431527-09-1 1-phenyl-3-(o-methylphenyl)-2,3-epoxy-1-propanone 
• 1321921-47-4 4-(2-methylphenyl)-6-phenyl-3,4-dihydropyrimidine-2(1H)-thione 
• 1283749-63-2 N-(2-chloro-3-oxo-3-phenyl-1-(o-tolyl)propyl)-4-methylbenzenesulfonamide 
• 1246850-18-9 N-((1R,2R)-2-bromo-3-oxo-3-phenyl-1-o-tolylpropyl)-4-methylbenzenesulfonamide 
• 1206190-28-4 5-(2-methylphenyl)-3-phenyl-4,5-dihydro-1H-pyrazole-1-carboximidamide 
• 1255771-99-3 tert-butyl 5-(2-methylphenyl)-3-phenyl-4,5-dihydro-1H-pyrazole-1-carboxylate 

Relevant articles and documents

Selective C-C bonds formation, N-alkylation and benzo[d]imidazoles synthesis by a recyclable zinc composite

Earth abundant metals are much less expensive, promising, valuable metals and could be served as catalysts for the borrowing hydrogen reaction, dehydrogenation and heterocycles synthesis, instead of noble metals. The uniformly dispersed zinc composites were designed, synthesized and carefully characterized by means of XPS, EDS, TEM and XRD. The resulting zinc composite showed good catalytic activity for the N-alkylation of amines with amines, ketones with alcohols in water under base-free conditions, while unsaturated carbonyl compounds could also be synthesized by tuning the reaction conditions. Importantly, it was the first time to realize the synthesis of 2-aryl-1H-benzo[d]imidazole derivatives by using this zinc composite under green conditions. Meanwhile, this zinc catalyst could be easily recovered and reused for at least five times.

Iridium and copper supported on silicon dioxide as chemoselective catalysts for dehydrogenation and borrowing hydrogen reactions

High active ligand usually plays an important role during catalysis and synthesis chemistry. A new and efficient benzotriazole-pyridinyl-silane ligand (BPS) was designed, and the corresponding iridium and copper catalysts were synthesized and thoroughly characterized by means of EDS, TEM, and XPS. The resulting iridium composite revealed excellent catalytic activity for the reaction of tert-butanesulfinamide with benzyl alcohols, while copper catalyst could realize the synthesis of unsaturated carbonyl compounds through the reaction of benzyl alcohols with ketones. This provided an efficient method for selective synthesis of unsaturated carbonyl compounds from benzyl alcohols and ketones in high yields with good recovery performance.

Rapid umpolung Michael addition of isatin N, N ′-cyclic azomethine imine 1,3-dipoles with chalcones

The umpolung Michael addition of isatin N,N′-cyclic azomethine imine 1,3-dipoles with chalcones is reported. The reaction could be finished within a very short time (0.3-2 min), with 3,3-disubstituted oxindole derivatives obtained in moderate to excellent yields with promising dr values. Unusual Michael adducts were obtained in moderate to high yields (26-98%) with low to high diastereoselectivities (0.8: 1 to 8.5: 1 dr). All the synthesized compounds (3, 3′, 4, 5, 5′, 7, 7′, 9 and 9′) were well characterized by FTIR, NMR, and mass spectral analyses and further confirmed by the single-crystal X-ray diffraction analysis of compounds 3aa and 4n.