1257661-32-7Relevant articles and documents
Enantioselective installation of adjacent tertiary benzylic stereocentres using lithiation-borylation-protodeboronation methodology. Application to the synthesis of bifluranol and fluorohexestrol
Roesner, Stefan,Blair, Daniel J.,Aggarwal, Varinder K.
, p. 3718 - 3723 (2015)
1,2-Diaryl ethanes bearing 1,2-stereogenic centres show interesting biological activity but their stereocontrolled synthesis has not been reported forcing a reliance of methods involving diastereomer and enantiomer separation. We have found that this clas
Full chirality transfer in the conversion of secondary alcohols into tertiary boronic esters and alcohols using lithiation-borylation reactions
Bagutski, Viktor,French, Rosalind M.,Aggarwal, Varinder K.
, p. 5142 - 5145 (2010/10/20)
New conditions, full transfer: Using MgBr2/MeOH as an additive now provides essentially 100 % retention of configuration in the lithiation-borylation reaction, thus leading to tertiary boronic esters (or tertiary alcohols) with exceptionally hi
