1257878-63-9

Basic information

• Product Name: 3-chloro-5-benzyl-1,2,4-oxadiazole
• Synonyms: 3-chloro-5-benzyl-1,2,4-oxadiazole
• CAS NO: 1257878-63-9
• Molecular Weight: 194.62
• Mol File: 1257878-63-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-chloro-5-benzyl-1,2,4-oxadiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-chloro-5-benzyl-1,2,4-oxadiazole(1257878-63-9)
• EPA Substance Registry System: 3-chloro-5-benzyl-1,2,4-oxadiazole(1257878-63-9)

Safety Data

• Hazardous Substances Data: 1257878-63-9(Hazardous Substances Data)

Upstream product

• 35604-35-4 5-benzyl[1.2.4]oxadiazol-3-ylamine 

Downstream Products

• 22819-07-4 3-Amino-5-benzyl-1H-1,2,4-triazole 

Relevant articles and documents

Synthesis of amino-1,2,4-triazoles by reductive ANRORC rearrangements of 1,2,4-oxadiazoles

The reaction of various 1,2,4-oxadiazoles with an excess of hydrazine in DMF has been investigated. 3-Amino-1,2,4-triazoles are produced through a reductive ANRORC pathway consisting of the addition of hydrazine to the 1,2,4-oxadiazole followed by ring-opening, ring-closure, and final reduction of the 3-hydroxylamino-1,2,4-triazole intermediate. The general applicability of 1,2,4-oxadiazoles ANRORC reactivity is demonstrated also in the absence of C(5)-linked electron-withdrawing groups.