1257983-13-3Relevant articles and documents
Synthesis of (2-Aminophenyl)(naphthalen-2-yl)methanones via Intramolecular Rearrangement of (E)-3-Styrylquinolin-4(1 H)-ones under Irradiation with 365 nm UV Light
Jing, Sisi,He, Yun,Wang, Tao,Zhang, Jin,Cheng, Anqi,Liang, Yong,Zhang, Zunting
, p. 1578 - 1582 (2018/06/26)
A highly efficient and environmentally friendly synthesis of (2-aminophenyl)(naphthalen-2-yl)methanones was developed. The (2-aminophenyl)(naphthalen-2-yl)methanone derivatives were obtained in high yields (up to 96%) by the irradiation of (E)-3-styrylquinolin-4(1 H)-ones in EtOH-H 2 O (7:1) with UV light (365 nm) at room temperature under Ar atmosphere. The demonstrated photoinduced intramolecular rearrangement has advantages over other transition-metal-catalyzed reactions, e.g. no requirement of additives, green solvent, broad substrate scope, and high atom efficiency.
New synthesis of (Z)-and (E)-3-styryl-4-quinolones
Seixas, Raquel S. G. R.,Silva, Artur M. S.,Cavaleiro, José A. S.
scheme or table, p. 2257 - 2262 (2010/11/04)
A novel and efficient route for the synthesis of (Z)-and (E)-3-styryl-4-quinolones is described. Wittig reaction of 4-(chloroquinoline- and quinolone)-3-carbaldehydes with benzylic ylides is the key transformation for this synthetic route. The (Z)-1-methyl-3-styryl-4-quinolone is obtained with high diastereoselectivity from the reaction of 1-methyl-4-quinolone-3- carbaldehyde; while (E)-3-styryl-4-quinolone is prepared through the Wittig reaction of 4-chloroquinoline-3-carbaldehyde followed by acid hydrolysis. Both synthetic routes are efficient regardless of the substituents on the benzylic ylides. Georg Thieme Verlag Stuttgart - New York.
