1260507-08-1

Basic information

• Product Name: 2(1H)-isoquinolinecarboxylic acid-3,4-dihydro-1-(2,4,6-trimethoxyphenyl)-phenylmethyl ester
• Synonyms: 2(1H)-isoquinolinecarboxylic acid-3,4-dihydro-1-(2,4,6-trimethoxyphenyl)-phenylmethyl ester
• CAS NO: 1260507-08-1
• Molecular Weight: 433.504
• Mol File: 1260507-08-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2(1H)-isoquinolinecarboxylic acid-3,4-dihydro-1-(2,4,6-trimethoxyphenyl)-phenylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2(1H)-isoquinolinecarboxylic acid-3,4-dihydro-1-(2,4,6-trimethoxyphenyl)-phenylmethyl ester(1260507-08-1)
• EPA Substance Registry System: 2(1H)-isoquinolinecarboxylic acid-3,4-dihydro-1-(2,4,6-trimethoxyphenyl)-phenylmethyl ester(1260507-08-1)

Safety Data

• Hazardous Substances Data: 1260507-08-1(Hazardous Substances Data)

Upstream product

• 621-23-8 1,2,3-trimethoxybenzene 
• 1449307-87-2 benzyl 1-(tert-butylperoxy)-3,4-dihydroisoquinoline-2(1H)-carboxylate 
• 142266-67-9 N-benzyloxycarbonyl-1,2,3,4-tetrahydroisoquinoline 

Downstream Products

• 1449308-12-6 1-(2,4,6-trimethoxyphenyl)-1,2,3,4-tetrahydroisoquinoline 

Relevant articles and documents

Synergistic effect of ketone and hydroperoxide in Bronsted acid catalyzed oxidative coupling reactions

Waste not wasted: A mechanistic study of the autoxidative coupling of xanthene with cyclopentanone uncovered an autoinductive effect of the waste product hydrogen peroxide. It generates radicals in the presence of acid and ketones, which accelerate the reaction by providing an additional pathway to the reactive hydroperoxide intermediate. This discovery could be applied to achieve other Bronsted acid catalyzed oxidative coupling reactions.

Direct functionalization of (Un)protected tetrahydroisoquinoline and isochroman under iron and copper catalysis: Two metals, two mechanisms

A highly facile, straightforward synthesis of 1-(3-indolyl)- tetrahydroisoquinolines was developed using either simple copper or iron catalysts. N-protected and unprotected tetrahydroisoquinolines (THIQ) could be used as starting materials. Extension of t