142266-67-9

Basic information

• Product Name: benzyl 3,4-dihydroisoquinoline-2(1H)-carboxylate
• Synonyms: benzyl 3,4-dihydroisoquinoline-2(1H)-carboxylate
• CAS NO: 142266-67-9
• Molecular Formula: C₁₇H₁₇NO₂
• Molecular Weight: 267.32238
• Mol File: 142266-67-9.mol
• Article Data: 11

Chemical Properties

• Appearance: /
• CAS DataBase Reference: benzyl 3,4-dihydroisoquinoline-2(1H)-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl 3,4-dihydroisoquinoline-2(1H)-carboxylate(142266-67-9)
• EPA Substance Registry System: benzyl 3,4-dihydroisoquinoline-2(1H)-carboxylate(142266-67-9)

Safety Data

• Hazardous Substances Data: 142266-67-9(Hazardous Substances Data)

Upstream product

• 191545-91-2 1,2,3,4-tetrahydro-2-benzyloxycarbonyl-4-phenylthioisoquinoline 
• 91-21-4 1,2,3,4-tetrahydroisoquinoline 
• 124-38-9 carbon dioxide 
• 100-51-6 benzyl alcohol 
• 14099-81-1 1,2,3,4-tetrahydroisoquinoline 
• 501-53-1 benzyl chloroformate 
• 66859-95-8 benzylidene-(2-phenylsulfanyl-ethyl)-amine 
• 67747-34-6 benzyl[2-(phenylsulfanyl)ethyl]amine 
• 100-52-7 benzaldehyde 
• 191545-78-5 N-benzyloxycarbonyl-N-benzyl-2-(phenylsulfinyl)ethylamine 
• 504-31-4 pyran-2-one 
• 138350-92-2 tert-butyl 1,2,3,4-tetrahydroisoquinoline-2-carboxylate 

Downstream Products

• 82342-56-1 N-benzoyl-1,2,3,4-tetrahydroisoquinoline 
• 14028-67-2 N-acetyl-1,2,3,4-tetrahydroisoquinoline 
• 91-21-4 1,2,3,4-tetrahydroisoquinoline 
• 908249-09-2 N-benzyloxycarbonyl-1-phenyl-1,2,3,4-tetrahydroisoquinoline 
• 908249-10-5 N-benzyloxycarbonyl-1-(2-methylphenyl)-1,2,3,4-tetrahydroisoquinoline 
• 908249-11-6 N-benzyloxycarbonyl-1-(2,6-dimethylphenyl)-1,2,3,4-tetrahydroisoquinoline 
• 610296-41-8 1-(2-methylphenyl)-1,2,3,4-tetrahydroisoquinoline 
• 22990-19-8 1-phenyl-1,2,3,4-tetrahydroisoquinoline 
• 1260506-80-6 phenylmethyl-1-(1H-indol-3-yl)-3,4-dihydroisoquinoline-2(1H)-carboxylate 
• 1260507-08-1 2(1H)-isoquinolinecarboxylic acid-3,4-dihydro-1-(2,4,6-trimethoxyphenyl)-phenylmethyl ester 
• 1449307-88-3 benzyl 1-(2,4-dimethoxyphenyl)-3,4-dihydroisoquinoline-2(1H)-carboxylate 
• 1449307-89-4 benzyl 1-(4-methoxyphenyl)-3,4-dihydroisoquinoline-2(1H)-carboxylate 
• 1449307-90-7 benzyl 1-(2,4,6-trihydroxyphenyl)-3,4-dihydroisoquinoline-2(1H)-carboxylate 
• 1449307-91-8 benzyl 1-(2-hydroxynaphthalen-1-yl)-3,4-dihydroisoquinoline-2(1H)-carboxylate 

Relevant articles and documents

Generation and regioselective trapping of a 3,4-piperidyne for the synthesis of functionalized heterocycles

We report the generation of the first 3,4-piperidyne and its use as a building block for the synthesis of annulated piperidines. Experimental and computational studies of this intermediate are disclosed, along with comparisons to the well-known 3,4-pyridyne. The distortion/interaction model is used to explain the observed regioselectivities.

Aerobic α-Oxidation of N-Substituted Tetrahydroisoquinolines to Dihydroisoquinolones via Organo-photocatalysis

An efficient visible-light-induced α-oxidation of N-substituted tetrahydroisoquinolines to dihydroisoquinolones has been developed using eosin Y as an organo-photocatalyst and oxygen as a green oxidant. The reactions were carried out under mild reaction conditions; the desired dihydroisoquinolones were obtained in up to 96% yield at room temperature under oxygen atmosphere. This transformation provides a convenient route to dihydroisoquinolones with a wide range of substrates. (Figure presented.).

Tropylium-Promoted Oxidative Functionalization of Tetrahydroisoquinolines

Structural modification of the tetrahydroisoquinoline (THIQ) framework is of significant interest to organic chemists due to its central role in heterocyclic and medicinal chemistry. Here we demonstrate an efficient metal-free method for the oxidative fun