1261225-48-2

Basic information

• Product Name: [3-(1S,3R)-benzyloxycarbonylaminocyclohexyl]-1-carbamic acid tertbutyl ester
• Synonyms: [3-(1S,3R)-benzyloxycarbonylaminocyclohexyl]-1-carbamic acid tertbutyl ester
• CAS NO: 1261225-48-2
• Molecular Weight: 348.442
• Mol File: 1261225-48-2.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 507.4±40.0 °C(Predicted)
• Density: 1.13±0.1 g/cm3(Predicted)
• CAS DataBase Reference: [3-(1S,3R)-benzyloxycarbonylaminocyclohexyl]-1-carbamic acid tertbutyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [3-(1S,3R)-benzyloxycarbonylaminocyclohexyl]-1-carbamic acid tertbutyl ester(1261225-48-2)
• EPA Substance Registry System: [3-(1S,3R)-benzyloxycarbonylaminocyclohexyl]-1-carbamic acid tertbutyl ester(1261225-48-2)

Safety Data

• Hazardous Substances Data: 1261225-48-2(Hazardous Substances Data)

Usage

General Description

[3-(1S,3R)-benzyloxycarbonylaminocyclohexyl]-1-carbamic acid tertbutyl ester is a chemical compound with the molecular formula C25H31N3O5. It is a carbamic acid ester that contains a cyclohexylamino group, a benzyloxycarbonyl group, and a tert-butyl ester group. [3-(1S,3R)-benzyloxycarbonylaminocyclohexyl]-1-carbamic acid tertbutyl ester has potential applications in pharmaceutical research and chemical synthesis, as it may possess biological activity or serve as a synthetic building block for more complex molecules. Additionally, it is important to handle and store this compound with care, as it may pose health and environmental hazards if not managed properly.

Upstream product

• 218772-92-0 (±)-cis-3-((tert-butoxycarbonyl)amino)cyclohexanecarboxylic acid 
• 347186-01-0 N-(3-aminocyclohexyl)(t-butoxy)carboxamide 
• 501-53-1 benzyl chloroformate 
• 100-51-6 benzyl alcohol 
• 222530-39-4 (1R,3S)-3-(tert-butoxycarbonylamino)aminocyclohexanecarboxylic acid 

Downstream Products

• 1259278-17-5 tert-butyl N-[(1R,3S)-3-aminocyclohexyl]carbamate 
• 1222709-28-5 ((1S,3R)-3-aminocyclohexyl)benzylcarbamate hydrochloride 
• 1223158-00-6 benzyl ((1R,3S)-3-aminocyclohexylamine)carboxylate 

Relevant articles and documents

CYCLOALKANE-1,3-DIAMINE DERIVATIVE

The present invention provides a compound or a pharmaceutically acceptable salt thereof having an inhibitory action on the interaction between menin and an MLL protein. The compound represented by the formula (1) or a pharmaceutically acceptable salt thereof. wherein, in the formula (1), the dotted circle, R1, R2, R3, R4, R5, R6, R7, R8, Ring Q1, W, m and n are each as defined in the description.

HETEROCYCLIC INDOLES FOR USE IN INFLUENZA VIRUS INFECTION

The current invention relates to a compound of formula (I) which can be used for the treatment of, or against viral influenza infections.

POLYCYCLIC INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7)

The present invention provides novel compounds of Formula (I), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled derivatives, prodrugs, and compositions thereof. Also provided are methods and kits involving the inventive compounds or compositions for treating or preventing proliferative diseases (e.g., cancers (e.g., leukemia, lymphoma, melanoma, multiple myeloma, breast cancer, Ewing' s sarcoma, osteosarcoma, brain cancer, neuroblastoma, lung cancer), benign neoplasms, angiogenesis, inflammatory diseases, autoinflammatory diseases, and autoimmune diseases) in a subject. Treatment of a subject with a proliferative disease using a compound or composition of the invention may inhibit the aberrant activity of a kinase, such as a cyclin-dependent kinase (CDK) (e.g., cyclin-dependent kinase 7 (CDK7), cyclin-dependent kinase 12 (CDK12), or cyclin-dependent kinase 13 (CDK13)), and therefore, induce cellular apoptosis and/or inhibit transcription in the subject.