1259278-17-5 Usage
Description
(1R,3S)-3-amino-1-(Boc-amino)cyclohexane is a cyclohexane derivative with a molecular formula of C10H20N2O2. It features an amino group and a Boc-protected amino group attached to the carbon atoms at positions 3 and 1, respectively. (1r,3s)-3-amino-1-(boc-amino)cyclohexane is known for its versatile reactivity and structural properties, making it a valuable building block in the synthesis of pharmaceuticals and agrochemicals. The Boc protecting group allows for mild deprotection conditions, enhancing its utility as an intermediate in organic synthesis. Its stereochemistry, characterized by a cis-1,3 relationship between the functional groups, further contributes to its applicability in organic chemistry.
Uses
Used in Pharmaceutical Synthesis:
(1R,3S)-3-amino-1-(Boc-amino)cyclohexane serves as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure and reactivity enable the development of new drugs with specific therapeutic properties.
Used in Agrochemical Production:
In the agrochemical industry, (1R,3S)-3-amino-1-(Boc-amino)cyclohexane is utilized as a building block for the creation of novel compounds with pesticidal or herbicidal activities, contributing to more effective crop protection strategies.
Used as an Organic Synthesis Intermediate:
Owing to its Boc-protected amino group and the ability to undergo mild deprotection, (1R,3S)-3-amino-1-(Boc-amino)cyclohexane is an ideal intermediate for organic synthesis. It facilitates the synthesis of complex organic molecules with potential applications in various fields.
Used in Stereoselective Synthesis:
(1r,3s)-3-amino-1-(boc-amino)cyclohexane's stereochemistry, with a cis-1,3 relationship between its functional groups, makes it a useful agent in stereoselective synthesis. This allows for the creation of enantiomerically pure compounds, which are essential in many biologically active molecules and pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 1259278-17-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,9,2,7 and 8 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1259278-17:
(9*1)+(8*2)+(7*5)+(6*9)+(5*2)+(4*7)+(3*8)+(2*1)+(1*7)=185
185 % 10 = 5
So 1259278-17-5 is a valid CAS Registry Number.
1259278-17-5Relevant articles and documents
BCAT MODULATION
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, (2021/01/29)
This disclosure relates to, in part, the treatment of an organic acidemia in a subject in need thereof via administration of a therapeutically effective amount of compounds that inhibit BCAT2. The disclosure also relates to, in part, methods for identifying a candidate compound for treatment of organic acidemias.
Development of a Scalable Synthesis of an Azaindolyl-Pyrimidine Inhibitor of Influenza Virus Replication
Liang, Jianglin,Cochran, John E.,Dorsch, Warren A.,Davies, Ioana,Clark, Michael P.
, p. 965 - 969 (2016/06/09)
A scalable, asymmetric route for the synthesis of the influenza virus replication inhibitor 2 is presented. The key steps include an enzymatic desymmetrization of cis-1,3-cyclohexanediester in 99% yield and 96% ee, SNAr displacement of a methanesulfinylpyrimidine, and a Curtius rearrangement to form a morpholinyl urea. This high-yielding route allowed us to rapidly synthesize hundreds of grams of 2 in 99% purity to support in vivo studies.
SUBSTITUTED PYRIMIDINE COMPOUNDS, COMPOSITIONS AND MEDICINAL APPLICATIONS THEREOF
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Paragraph 000234, (2015/03/13)
The present disclosure relates to pyrimidine compounds of formula (I), their stereoisomers, tautomers, pharmaceutically acceptable salts, polymorphs, solvates, and hydrates thereof. The present disclosure also relates to process of preparation of these pyrimidine compounds, and to pharmaceutical compositions containing them. The compounds of the present disclosure are useful in the treatment, prevention or suppression of diseases and disorders mediated by epidermal growth factor receptor (EGFR) family kinases.
