126538-81-6

Basic information

• Product Name: 5-broMo-6-(trifluoroMethyl)pyriMidin-4-ol
• Synonyms: 5-broMo-6-(trifluoroMethyl)pyriMidin-4-ol;5-BroMo-6-(trifluoroMethyl)pyriMidin-4(1H)-one;5-bromo-6-(trifluoromethyl)-4(3H)-Pyrimidinone;5-Bromo-6-trifluoromethyl-3H-pyrimidin-4-one
• CAS NO: 126538-81-6
• Molecular Formula: C5H2BrF3N2O
• Molecular Weight: 242.9813896
• Mol File: 126538-81-6.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 5-broMo-6-(trifluoroMethyl)pyriMidin-4-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 5-broMo-6-(trifluoroMethyl)pyriMidin-4-ol(126538-81-6)
• EPA Substance Registry System: 5-broMo-6-(trifluoroMethyl)pyriMidin-4-ol(126538-81-6)

Safety Data

• Hazardous Substances Data: 126538-81-6(Hazardous Substances Data)

Usage

General Description

5-bromo-6-(trifluoromethyl)pyrimidin-4-ol is a chemical compound with the molecular formula C5H3BrF3N3O. It is a pyrimidine derivative with a bromine atom and a trifluoromethyl group attached to the pyrimidine ring, and a hydroxyl group at the 4-position. 5-broMo-6-(trifluoroMethyl)pyriMidin-4-ol is of interest in medicinal and agricultural research due to its potential as a pharmaceutical intermediate or agrochemical agent. It may have biological activity that is relevant to drug discovery and development, as well as potential applications in crop protection. As a heterocyclic compound, it may also have unique reactivity and potential for use in synthetic chemistry.

Upstream product

• 1546-78-7 4-trifluoromethyl-1,6-dihydropyrimidine-6-oxide 
• 368-54-7 2-sulfanylidene-6-(trifluoromethyl)-2,3-dihydropyrimidin-4(1H)-one 

Downstream Products

• 785777-94-8 4,5-dibromo-6-(trifluoromethyl)pyrimidine 
• 425392-76-3 5-bromo-4-chloro-6-(trifluoromethyl)pyrimidine 
• 1591827-34-7 3-chloro-5-((1-((5-(fluoromethyl)-6-methoxypyridazin-3-yl)methyl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile 
• 1591824-04-2 3-chloro-5-((1-((5-(fluoromethyl)-6-oxo-1,6-dihydropyridazin-3-yl)methyl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile 
• 1591827-42-7 3-((1-((5-bromo-1-(4-methoxybenzyl)-6-oxo-1,6-dihydropyridazin-3-yl)methyl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)-5-chlorobenzonitrile 
• 1591827-43-8 3-chloro-5-((1-((1-(4-methoxybenzyl)-6-oxo-5-phenyl-1,6-dihydropyridazin-3-yl)methyl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile 
• 1591824-21-3 3-chloro-5-((6-oxo-1-((6-oxo-5-phenyl-1,6-dihydropyridazin-3-yl)methyl)-4-(trifluoro methyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile 
• 1591826-99-1 3-chloro-5-(1-(4-methoxybenzyl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yloxy)benzonitrile 
• 1591827-49-4 3-chloro-5-((1-((5-(4-fluorophenyl)-6-oxo-1-(tetrahydro-2H-pyran-2-yl)-1,6-dihydropyridazin-3-yl)methyl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile 
• 1591825-43-2 3-chloro-5-((1-((5-(4-fluorophenyl)-6-oxo-1,6-dihydropyridazin-3-yl)methyl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile 
• 1591827-00-7 3-chloro-5-((6-oxo-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile 
• 1591827-50-7 3-chloro-5-((1-((5-(6-fluoropyridin-3-yl)-1-(4-methoxybenzyl)-6-oxo-1,6-dihydropyridazin-3-yl)methyl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile 
• 1591825-45-4 3-chloro-5-((1-((5-(6-fluoropyridin-3-yl)-6-oxo-1,6-dihydropyridazin-3-yl)methyl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile 
• 1591823-63-0 3-chloro-5-((6-oxo-1-((5-oxo-5,6-dihydropyrido[2,3-d]pyridazin-8-yl)methyl)-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile 

Relevant articles and documents

PRODRUGS OF HIV REVERSE TRANSCRIPTASE INHIBITORS

Compounds of Formula I are described: wherein R1 and R2 are defined herein. The compounds of Formula I are useful in the inhibition of HIV reverse transcriptase, the prophylaxis and treatment of infection by HIV, and the prophylaxis, delay in the onset or progression, and treatment of AIDS. The compounds can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.

NOVEL HERBICIDES

Compounds of formula I: wherein R1, R2, R3, R4, m, R5, R6, n and Y are as defined in claim 1; or N-oxides, salts and optical isomers thereof. Furthermore, the present invention relates to processes for preparing compounds of formula (I), to herbicidal compositions comprising them and to methods of using them to control plants or to inhibit plant growth.

Novel compounds

Insecticidal compounds of formula (I) STR1 wherein R1 and R2 are independently selected from halogen or nitro; R3 and R4 are independently selected from hydrogen or halogen; R5 is hydrogen, halogen or