1546-78-7 Usage
Description
4-Hydroxy-6-(trifluoromethyl)pyrimidine, also known as 6-(Trifluoromethyl)-4-pyrimidinol, is a pyrimidine derivative that serves as a heterocyclic building block in chemical synthesis. It is characterized by its white powder form and is known for its potential applications in various industries due to its unique chemical properties.
Uses
Used in Chemical Synthesis:
4-Hydroxy-6-(trifluoromethyl)pyrimidine is used as a building block in chemical synthesis for the development of various products. Its heterocyclic structure allows for the creation of complex molecules with diverse applications.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-Hydroxy-6-(trifluoromethyl)pyrimidine is used as a key intermediate in the synthesis of 10-[3-(6-trifluoromethyl-pyrimidin-4-yloxy)-propoxy]-(20S)-camptothecin. 4-Hydroxy-6-(trifluoromethyl)pyrimidine has potential applications in cancer treatment due to its ability to inhibit topoisomerase I, a crucial enzyme in DNA replication.
Used in Development of New Products:
The unique properties of 4-Hydroxy-6-(trifluoromethyl)pyrimidine make it a valuable component in the development of new products across various industries. Its versatility as a building block allows for the creation of innovative compounds with specific attributes tailored to meet the needs of different applications.
Synthesis Reference(s)
Journal of the American Chemical Society, 80, p. 5744, 1958 DOI: 10.1021/ja01554a041
Check Digit Verification of cas no
The CAS Registry Mumber 1546-78-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,5,4 and 6 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1546-78:
(6*1)+(5*5)+(4*4)+(3*6)+(2*7)+(1*8)=87
87 % 10 = 7
So 1546-78-7 is a valid CAS Registry Number.
InChI:InChI=1/C5H3F3N2O/c6-5(7,8)3-1-4(11)10-2-9-3/h1-2H,(H,9,10,11)
