126541-80-8

Basic information

• Product Name: 3-Acetamino-4-(trifluormethyl)benzoesaeure
• Synonyms: 3-Acetamino-4-(trifluormethyl)benzoesaeure
• CAS NO: 126541-80-8
• Molecular Weight: 247.174
• Mol File: 126541-80-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Acetamino-4-(trifluormethyl)benzoesaeure(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Acetamino-4-(trifluormethyl)benzoesaeure(126541-80-8)
• EPA Substance Registry System: 3-Acetamino-4-(trifluormethyl)benzoesaeure(126541-80-8)

Safety Data

• Hazardous Substances Data: 126541-80-8(Hazardous Substances Data)

Upstream product

• 116965-16-3 3-nitro-4-(trifluoromethyl)benzoic acid 
• 455-24-3 4-trifluoromethylbenzoic acid 
• 108-24-7 acetic anhydride 
• 125483-00-3 3-amino-4-(trifluoromethyl)benzoic acid 

Downstream Products

• 126541-83-1 3-Acetamino-6-nitro-4-(trifluormethyl)benzoesaeure 

Relevant articles and documents

Demethyl(trifluoromethyl)actinomycins

The synthesis of new 4-(trifluoromethyl)benzoic acid derivatives 2-10 and their coupling with amino acids and peptides 12, 13, 15 is described.They serve as precursors for the synthesis of the hitherto unknown demethyl(trifluoromethyl)actinocin dimethyl esters 11, demethyl-trifluoromethyl-actinocinyl peptides 14, 16, 18 and the demethyl-trifluoromethyl-actinomycins 17.Although spacially comparable with the methyl residues, the 4- and 6-trifluoromethyl groups have unexpected strong influences on the antibiotic and cytostatic properties of the actinomycins.The CH3/CF3 exchange makes it possible to bring NMR-analytically useful hetero nuclei into the centre of the actinomycin/DNA complex (Figure 1).