1265815-86-8

Basic information

• Product Name: 3,3,3-trifluoro-2-hydroxy-2-(7-phenyl-1H-indol-3-yl)-propionic acid ethyl ester
• CAS NO: 1265815-86-8
• Molecular Weight: 363.336
• Mol File: 1265815-86-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3,3,3-trifluoro-2-hydroxy-2-(7-phenyl-1H-indol-3-yl)-propionic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3,3-trifluoro-2-hydroxy-2-(7-phenyl-1H-indol-3-yl)-propionic acid ethyl ester(1265815-86-8)
• EPA Substance Registry System: 3,3,3-trifluoro-2-hydroxy-2-(7-phenyl-1H-indol-3-yl)-propionic acid ethyl ester(1265815-86-8)

Safety Data

• Hazardous Substances Data: 1265815-86-8(Hazardous Substances Data)

Upstream product

• 1863-21-4 7-(phenyl)-1H-indole 
• 13081-18-0 ethyl-3,3,3-trifluoropyruvate 

Relevant articles and documents

Catalyst-free and catalytic Friedel-Crafts alkylations of indoles in Solkane 365mfc, an environmentally benign alternative solvent

Solkane 365mfc is a proven environmentally benign alternative solvent for catalyst-free Friedel-Crafts (F-C) alkylations of indoles with trifluoropyruvate and glyoxylate. Their enantioselective variants are also achieved by virtue of the high-affinity of fluorous cinchona alkaloids catalysts to Solkane 365mfc to provide F-C adducts in excellent yields with good to excellent ees (up to 96% ee).