1268364-24-4

Basic information

• Product Name: C₁₀H₁₁FO₄
• Synonyms: C₁₀H₁₁FO₄
• CAS NO: 1268364-24-4
• Molecular Weight: 214.193
• Mol File: 1268364-24-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₁₀H₁₁FO₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₀H₁₁FO₄(1268364-24-4)
• EPA Substance Registry System: C₁₀H₁₁FO₄(1268364-24-4)

Safety Data

• Hazardous Substances Data: 1268364-24-4(Hazardous Substances Data)

Upstream product

• 79418-78-3 3-fluoro-4-hydroxy-5-methoxybenzaldehyde 
• 107-30-2 chloromethyl methyl ether 

Downstream Products

• 1268364-04-0 C₁₀H₁₃FO₄ 

Relevant articles and documents

Scalable Total Synthesis of (+)- And (-)-Codonopiloneolignanin A via Ti(IV)/NHC Cooperative Control Highly Enantioselective Dimerization of Multisubstituted Cinnamaldehyde

The first gram-scale asymmetric total synthesis of (+)- and (-)-codonopiloneolignanin A has been achieved from multisubstituted cinnamaldehyde in four steps with 37% overall yield. The synthetically challenging tricyclic [5, 3, 0, 03,8] decane skeleton was efficiently constructed via a highly enantioselective dimerization of multisubstituted cinnamaldehyde, followed by a sequence of cascade reactions including Prins cyclization, cation mediated cyclization, and deprotection. Furthermore, the scope of NHC-catalyzed/Ti(IV)-mediated synergistic control multisubstituted cinnamaldehyde dimerization was investigated. Significantly, the bioactivity of codonopiloneolignanin A and its enantiomer, particularly scarce in nature, was tested and showed good anticancer activity.