1268524-63-5Relevant articles and documents
A copper(I) isonitrile complex as a heterogeneous catalyst for azide-alkyne cycloaddition in water
Liu, Meina,Reiser, Oliver
, p. 1102 - 1105 (2011/04/24)
A structurally well-defined copper(I) isonitrile complex is shown to be an efficient, heterogeneous catalyst for the Huisgen azide-alkyne 1,3-dipolar cycloaddition under mild conditions in water. Notably, this catalyst can also be utilized in a three-component reaction of halides, sodium azide and alkynes to form 1,4-disubstituted 1,2,3-triazoles in high yields. Furthermore, it can be readily recovered by precipitation and filtration and recycled for at least five runs without significant loss of activity.(Figure Presented)