126921-19-5

Basic information

• Product Name: 1H-Indole-3-carbonylchloride, 1-methyl-
• Synonyms: 1-Methyl-1H-indole-3-carbonylchloride
• CAS NO: 126921-19-5
• Molecular Formula: C₁₀H₈ClNO
• Molecular Weight: 193.63
• Product Categories: ACIDHALIDE
• Mol File: 126921-19-5.mol
• Article Data: 35

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1H-Indole-3-carbonylchloride, 1-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole-3-carbonylchloride, 1-methyl-(126921-19-5)
• EPA Substance Registry System: 1H-Indole-3-carbonylchloride, 1-methyl-(126921-19-5)

Safety Data

• Hazardous Substances Data: 126921-19-5(Hazardous Substances Data)

Usage

Description

1H-Indole-3-carbonylchloride, 1-methylis an organic compound that serves as a key intermediate in the synthesis of various pharmaceuticals and organic compounds. It is characterized by its indole ring structure with a carbonyl chloride group attached to the 3-position and a methyl group at the 1-position. This unique structure endows it with reactivity and properties that make it a valuable building block in organic synthesis.
Used in Pharmaceutical Industry:
1H-Indole-3-carbonylchloride, 1-methylis used as a reactant for the preparation of indolo[2,3-a]pyrimido[5,4-c]carbazole derivatives, which are of significant interest due to their potential as anti-cancer agents. The incorporation of this compound into the synthesis process allows for the development of novel and more effective cancer treatments, targeting specific molecular pathways and mechanisms involved in tumor growth and progression.

Upstream product

• 32387-21-6 1-methyl-3-indolecarboxylic acid 
• 79-37-8 oxalyl dichloride 
• 3416-93-1 2-(4,5-Dihydro-1,3-oxazol-2-yl)aniline 
• 942-24-5 3-methoxycarbonylindole 
• 108438-43-3 methyl 1-methyl-1H-indole-3-carboxylate 
• 487-89-8 Indole-3-carboxaldehyde 
• 19012-03-4 N-methyl-3-formylindole 
• 120-72-9 indole 
• 603-76-9 1-methylindole 
• 318-54-7 2,2,2-trifluoro-1-(1-methyl-1H-indol-3-yl)ethan-1-one 

Downstream Products

• 82414-31-1 1-methyl-1H-indole-3-carboxylic acid phenylamide 
• 82430-60-2 1-Methyl-1H-indole-3-carboxylic acid (2,4,6-trimethyl-phenyl)-amide 
• 142894-64-2 1-Methyl-1H-indole-3-carboxylic acid ((1R,3R,5S)-9-benzyl-9-aza-bicyclo[3.3.1]non-3-yl)-amide 
• 871843-09-3 4,5-bis(1-Methyl-1H-indol-3-yl)-1,2-dihydropyrazol-3-one 
• 1026904-01-7 2-((S)-1-Benzyloxycarbonylamino-3-methyl-butyl)-5-(1-methyl-1H-indol-3-yl)-thiazole-4-carboxylic acid 
• 173962-09-9 2-((S)-1-Benzyloxycarbonylamino-3-methyl-butyl)-5-(1-methyl-1H-indol-3-yl)-oxazole-4-carboxylic acid ethyl ester 
• 173962-10-2 2-((S)-1-Benzyloxycarbonylamino-3-methyl-butyl)-5-(1-methyl-1H-indol-3-yl)-thiazole-4-carboxylic acid ethyl ester 
• 1027532-35-9 (R)-2-{[2-((S)-1-Benzyloxycarbonylamino-3-methyl-butyl)-5-(1-methyl-1H-indol-3-yl)-oxazole-4-carbonyl]-amino}-3-pyridin-2-yl-propionic acid ethyl ester 
• 1027306-66-6 (R)-2-{[2-((S)-1-Benzyloxycarbonylamino-3-methyl-butyl)-5-(1-methyl-1H-indol-3-ylmethyl)-oxazole-4-carbonyl]-amino}-3-pyridin-2-yl-propionic acid ethyl ester 
• 848853-49-6 N-[(3'-bromo-4'-methoxy-1,1'-biphenyl-4-yl)methyl]-N,1-dimethyl-1H-indole-3-carboxamide 
• 1198408-67-1 C₁₆H₁₃ClN₂O 
• 1280723-14-9 methyl 3-(4-methoxyphenyl)-2-(1-methyl-1H-indole-3-carbonyl)acrylate 
• 1280722-75-9 methyl 2-(4-methoxyphenyl)-1-(1-methyl-1H-indole-3-carbonyl)cyclopropanecarboxylate 

Relevant articles and documents

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