126931-32-6

Basic information

• Product Name: tert-Butyl 4-(3-hydroxy-1-propyl)benzoate
• Synonyms: tert-Butyl 4-(3-hydroxy-1-propyl)benzoate
• CAS NO: 126931-32-6
• Molecular Weight: 236.311
• Mol File: 126931-32-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: tert-Butyl 4-(3-hydroxy-1-propyl)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-Butyl 4-(3-hydroxy-1-propyl)benzoate(126931-32-6)
• EPA Substance Registry System: tert-Butyl 4-(3-hydroxy-1-propyl)benzoate(126931-32-6)

Safety Data

• Hazardous Substances Data: 126931-32-6(Hazardous Substances Data)

Upstream product

• 126931-31-5 methyl 3-<4-(tert-butoxycarbonyl)phenyl>propanoate 
• 86208-18-6 3-<4-(tert-butoxycarbonyl)phenyl>propionic acid 
• 169134-89-8 tert-butyl 4-(3-hydroxyprop-1-yn-1-yl)benzoate 
• 619-58-9 4-iodobenzoic acid 
• 120363-13-5 tert-butyl 4-iodobenzoate 
• 65874-27-3 4-(tert-butoxycarbonyl)benzaldehyde 
• 149325-50-8 ethyl 3-<4-(tert-butoxycarbonyl)phenyl>acrylate 
• 86208-17-5 3-(4-tert-butyloxycarbonylphenyl)propionic acid ethyl ester 
• 146943-27-3 methyl 3-<4-(tert-butoxycarbonyl)phenyl>propenoate 

Downstream Products

• 134373-00-5 tert-butyl 4-(4-methoxy-3-butenyl)benzoate 
• 134373-01-6 4-(4,4-Dicyano-3-dimethoxymethyl-butyl)-benzoic acid tert-butyl ester 
• 137281-39-1 4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl )ethyl]benzoic acid 
• 134373-06-1 4-[4,4-Dimethoxy-3-(2,4,6-triamino-pyrimidin-5-yl)-butyl]-benzoic acid tert-butyl ester 
• 146943-41-1 4-[3-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimidin-5-yl)-4,4-dimethoxy-butyl]-benzoic acid tert-butyl ester 
• 146943-43-3 N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]-pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid diethyl ester 
• 126931-33-7 tert-butyl 4-(3-bromopropyl)benzoate 
• 158214-27-8 (S)-2-{4-[3-(2,4-Diamino-6,7-dihydro-5H-cyclopentapyrimidin-5-yl)-propyl]-benzoylamino}-pentanedioic acid diethyl ester 
• 1053704-34-9 (S)-2-{4-[3-(2-Amino-4-hydroxy-6,7-dihydro-5H-cyclopentapyrimidin-5-yl)-propyl]-benzoylamino}-pentanedioic acid diethyl ester 
• 158214-23-4 tert-butyl 4-<3-(2-amino-6,7-dihydro-4-oxo-5H-cyclopentapyrimidin-5-yl)propyl>benzoate 
• 149325-53-1 tert-butyl 4-<3-(2,4-diamino-6,7-dihydro-5H-cyclopentapyrimidin-5-yl)propyl>benzoate 
• 158214-16-5 tert-butyl 4-<3-<2-(methoxycarbonyl)-3-oxocyclopentanyl>propyl>benzoate 
• 149325-54-2 4-<3-(2,4-diamino-6,7-dihydro-5H-cyclopentapyrimidin-5-yl)propyl>benzoic acid 
• 158214-25-6 4-<3-(2-amino-6,7-dihydro-4-oxo-5H-cyclopentapyrimidin-5-yl)propyl>benzoic acid 

Relevant articles and documents

Condensed pyrimidine derivative

A novel pyrimidine derivative having an excellent antitumor activity, which is represented by the following general formula (I) or a pharmacologically acceptable salt thereof: STR1 wherein R1 represents a hydroxyl or amino group; R2 represents a phenylene, pyridinediyl, thiendiyl, furandiyl or thiazoldiyl group, --CO2 R5 and --CO2 R6 may be the same or different from each other and each represents a carboxyl group or a carboxylic acid ester, the part STR2 A represents an oxygen atom, a group represented by the formula: STR3 (wherein R3 and R4 may be the same or different from each other and each represents a hydrogen or halogen atom or a hydrocarbon group which may be substituted, or alternatively R3 and R4 may be united to form an alkylidene group which may be substituted) or a group represented by the formula: STR4 (wherein R70 represents a hydrogen atom or a hydrocarbon group), and n is an integer of 1 to 3, provided that the compound in which R1 represents oxygen, and hydrogen is attached to nitrogen at 3-position is included in the above shown definition, a process for preparation the same, and an antitumor drug containing the same.

Synthesis and antitumor activities of novel 6-5 fused ring heterocycle antifolates: N-[4-[ω-(2-amino-4-substituted-6,7- dihydrocyclopenta[d]pyrimidin-5-yl)alkyl]benzoyl]-L-glutamic acids

Novel antifolates with a 6-5 fused ring system, 6,7- dihydrocyclopenta[d]pyrimidine, (3a,b and 4a,b) were synthesized on the basis of combined modification of the heterocycle and bridge regions of the folate molecule. The synthetic method involves (1) syn

Fused pyrimidines, their production and use

New fused pyrimidines of the general formula (I): STR1 wherein the ring A is a pyridine ring which may be hydrogenated or a benzene ring which may be hydrogenated, X is an amino group or a hydroxyl group, R1, R2, R3 and R