127141-20-2

Basic information

• Product Name: C₁₇H₁₆O₃
• Synonyms: C₁₇H₁₆O₃
• CAS NO: 127141-20-2
• Molecular Weight: 268.312
• Mol File: 127141-20-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: C₁₇H₁₆O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₇H₁₆O₃(127141-20-2)
• EPA Substance Registry System: C₁₇H₁₆O₃(127141-20-2)

Safety Data

• Hazardous Substances Data: 127141-20-2(Hazardous Substances Data)

Upstream product

• 106824-46-8 4,5-dimethoxy-2-(2-phenylethynyl)benzaldehyde 
• 5392-10-9 2-bromo-4,5-dimethoxybenzaldehyde 
• 536-74-3 phenylacetylene 
• 1607804-80-7 (4,5-dimethoxy-2-(phenylethynyl)phenyl)methanol 
• 531-88-4 5,6-dimethoxyphthalide 
• 618-31-5 benzylidene dibromide 

Downstream Products

• 127141-24-6 1-Benzyl-4,5-dimethoxy-11-oxa-tricyclo[6.2.1.0^2,7]undeca-2⁽⁷⁾,3,5,9-tetraene-9,10-dicarboxylic acid dimethyl ester 

Relevant articles and documents

Regio- and stereoselective intramolecular hydroalkoxylation of aromatic alkynols: an access to dihydroisobenzofurans under transition-metal-free conditions

An efficient, transition-metal-free method to synthesize dihydroisobenzofuran derivatives via intramolecular hydroalkoxylation of aromatic alkynols with the promotion of cesium carbonate has been developed. The reaction proceeds regioselectively with exclusive formation of 5-exo-dig product, and only Z-isomer of the new generated double bond is observed. This new protocol features with milder reaction conditions, more convenient operation and satisfactory selectivities.

Selective cyclization of alkynols and alkynylamines catalyzed by potassium tert-butoxide

Potassium tert-butoxide (t-BuOK) was found to be an effective catalyst for the cyclization of aromatic alkynols and alkynylamines. In the presence of 10 mol % t-BuOK, a range of alkynols were converted to the corresponding exo-cyclic enol ethers as pure Z