1271792-72-3

Basic information

• Product Name: (R,Z)-methyl 3-(4-methoxyphenyl)-3-(1-phenylethylamino)acrylate
• Synonyms: (R,Z)-methyl 3-(4-methoxyphenyl)-3-(1-phenylethylamino)acrylate
• CAS NO: 1271792-72-3
• Molecular Weight: 311.381
• Mol File: 1271792-72-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R,Z)-methyl 3-(4-methoxyphenyl)-3-(1-phenylethylamino)acrylate(CAS DataBase Reference)
• NIST Chemistry Reference: (R,Z)-methyl 3-(4-methoxyphenyl)-3-(1-phenylethylamino)acrylate(1271792-72-3)
• EPA Substance Registry System: (R,Z)-methyl 3-(4-methoxyphenyl)-3-(1-phenylethylamino)acrylate(1271792-72-3)

Safety Data

• Hazardous Substances Data: 1271792-72-3(Hazardous Substances Data)

Upstream product

• 3886-69-9 (R)-1-phenyl-ethyl-amine 
• 22027-50-5 methyl 3-(4-methoxybenzoyl)acetate 

Downstream Products

• 131791-82-7 methyl (-)-(3R)-3-amino-3-(4-methoxyphenyl)propanoate 

Relevant articles and documents

Triclorosilane-mediated stereoselective synthesis of β-amino esters and their conversion to highly enantiomerically enriched β-lactams

A highly stereoselective trichlorosilane-mediated reduction of N-benzyl enamines was developed; the combination of a low cost, easy to make metal-free catalyst and an inexpensive chiral auxiliary allowed to perform the reaction on substrates with different structural features often with total control of the stereoselectivity. By easy deprotection through hydrogenolysis followed by conversion of β-aminoester to 2-azetidinones, the synthesis of enantiomerically pure β-lactams (>98% e.e.) was successfully accomplished.