1271930-15-4 Usage
Description
Cinacalcet iMpurity 8, also known as N-[(3-Trifluoromethyl)phenyl)propyl] Cinacalcet, is an impurity of Cinacalcet Hydrochloride (C441800). It is a synthetically derived compound that is structurally similar to the parent drug, cinacalcet, which is used for the treatment of secondary hyperparathyroidism.
Used in Pharmaceutical Industry:
Cinacalcet iMpurity 8 is used as a reference material for quality control and analytical testing in the pharmaceutical industry. It helps ensure the purity, potency, and safety of cinacalcet hydrochloride, which is used in clinical trials for the treatment of secondary hyperparathyroidism. By monitoring the presence and levels of this impurity, researchers and manufacturers can maintain the quality and efficacy of the drug, ultimately benefiting patients undergoing treatment for this condition.
Check Digit Verification of cas no
The CAS Registry Mumber 1271930-15-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,7,1,9,3 and 0 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1271930-15:
(9*1)+(8*2)+(7*7)+(6*1)+(5*9)+(4*3)+(3*0)+(2*1)+(1*5)=144
144 % 10 = 4
So 1271930-15-4 is a valid CAS Registry Number.
1271930-15-4Relevant articles and documents
Method For The Preparation Of Cinacalcet And Intermediates And Impurities Thereof
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, (2012/01/13)
A method for the preparation of Cinacalcet is disclosed comprising treating (R)-1-naphthyl ethylamine with an aromatic aldehyde to form (1R)-1-(2-naphthyl)-N-(aryl methylene)ethanamine derivative of Formula (IV), which is further treated with 1-(3-halopropyl)-3-(trifluoromethyl)benzene of Formula (V) to obtain an iminium salt of Formula (VI), followed by hydrolysis to obtain Cinacalcet free base.
