1272672-25-9

Basic information

• Product Name: 2-chloro-7-hydroxy-1-[2'-hydroxy-3'-(methyloxy)-4-biphenylyl]-5-oxo-4,5-dihydro-1H-pyrrolo[3,2-b]pyridine-6-carbonitrile
• Synonyms: 2-chloro-7-hydroxy-1-[2'-hydroxy-3'-(methyloxy)-4-biphenylyl]-5-oxo-4,5-dihydro-1H-pyrrolo[3,2-b]pyridine-6-carbonitrile
• CAS NO: 1272672-25-9
• Molecular Weight: 407.813
• Mol File: 1272672-25-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-chloro-7-hydroxy-1-[2'-hydroxy-3'-(methyloxy)-4-biphenylyl]-5-oxo-4,5-dihydro-1H-pyrrolo[3,2-b]pyridine-6-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-7-hydroxy-1-[2'-hydroxy-3'-(methyloxy)-4-biphenylyl]-5-oxo-4,5-dihydro-1H-pyrrolo[3,2-b]pyridine-6-carbonitrile(1272672-25-9)
• EPA Substance Registry System: 2-chloro-7-hydroxy-1-[2'-hydroxy-3'-(methyloxy)-4-biphenylyl]-5-oxo-4,5-dihydro-1H-pyrrolo[3,2-b]pyridine-6-carbonitrile(1272672-25-9)

Safety Data

• Hazardous Substances Data: 1272672-25-9(Hazardous Substances Data)

Upstream product

• 5467-74-3 4-Bromophenylboronic acid 
• 1272673-94-5 ethyl 3-(acetylamino)-1-(4-bromophenyl)-1H-pyrrole-2-carboxylate 
• 1438835-17-6 ethyl 5-chloro-3-[(cyanoacetyl)amino]-1-[2'-hydroxy-3'-(methyloxy)-4-biphenylyl]-1H-pyrrole-2-carboxylate 
• 1272674-58-4 ethyl 3-amino-5-chloro-1-[2'-hydroxy-3'-(methyloxy)-4-biphenylyl]-1H-pyrrole-2-carboxylate 
• 1272673-93-4 ethyl 3-(acetylamino)-1H-pyrrole-2-carboxylate 
• 1272674-02-8 ethyl 1-(4-bromophenyl)-5-chloro-3-[(cyanoacetyl)amino]-1H-pyrrole-2-carboxylate 
• 1272674-01-7 ethyl 3-amino-1-(4-bromophenyl)-5-chloro-1H-pyrrole-2-carboxylate 
• 1272674-00-6 ethyl 3-(acetylamino)-1-(4-bromophenyl)-5-chloro-1H-pyrrole-2-carboxylate 
• 1272673-99-0 ethyl 3-(acetylamino)-5-chloro-1H-pyrrole-2-carboxylate 
• 259209-17-1 [2-hydroxy-3-(methyloxy)phenyl]boronic acid 
• 1272672-24-8 1-(4-bromophenyl)-2-chloro-7-hydroxy-5-oxo-4,5-dihydro-1H-pyrrolo[3,2-b]pyridine-6-carbonitrile 
• 252932-49-3 3-amino-2-ethoxycarbonylpyrrole hydrochloride 
• 252932-48-2 3-amino-2-ethoxycarbonylpyrrole 

Relevant articles and documents

Discovery of pyridones as oral AMPK direct activators

AMP-activated protein kinase (AMPK) is an evolutionarily conserved fuel-sensing enzyme that is activated in shortage of energy and suppressed in its surfeit. AMPK activation stimulates fatty acid oxidation, enhances insulin sensitivity, alleviates hypergl