127399-65-9

Basic information

• Product Name: 6-(benzyloxy)-5-methoxy-1-methyleneindan
• Synonyms: 6-(benzyloxy)-5-methoxy-1-methyleneindan
• CAS NO: 127399-65-9
• Molecular Weight: 266.34
• Mol File: 127399-65-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-(benzyloxy)-5-methoxy-1-methyleneindan(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(benzyloxy)-5-methoxy-1-methyleneindan(127399-65-9)
• EPA Substance Registry System: 6-(benzyloxy)-5-methoxy-1-methyleneindan(127399-65-9)

Safety Data

• Hazardous Substances Data: 127399-65-9(Hazardous Substances Data)

Upstream product

• 3199-70-0 6-(benzyloxy)-5-methoxy-1-indanone 
• 1779-49-3 Methyltriphenylphosphonium bromide 

Downstream Products

• 127399-67-1 9-(benzyloxy)-8-methoxy-1,4,5,6-tetrahydrobenzoquinolin-3(2H)-one 
• 127399-66-0 1,2,3,4-tetrahydro-7-(benzyloxy)-6-methoxy-2(1H)-naphthalenone 
• 127399-76-2 6-(benzyloxy)-5-methoxy-1-methylindene 

Relevant articles and documents

Monomethyl Ether Derivatives of 7,8-Dihydroxy- and 8,9-Dihydroxy-4-n-propyl-1,2,3,4,4a,5,6,10b-octahydrobenzoquinolines as Possible Products of Metabolism by Catechol-O-methyltransferase

In order to facilitate identification of possible metabolites arising from in vitro action of catechol-O-methyltransferase upon 7,8-dihydroxy- and 8,9-dihydroxy-4-n-propyl-1,2,3,4,4a,5,6,10b-octahydrobenzoquinolines (11, 12), all four possible monomethyl ether derivatives have been synthesized.Incubation of 11 and 12 with the enzyme revealed that the 8,9-dihydroxy positional isomer 12 (which contains the dopamine moiety held in the β conformation) but not the 7,8-dihydroxy isomer 11 (which holds the dopamine moiety in the α conformation) was a substrate for theenzyme.The sole detectable product of 12 was 8-hydroxy-9-methoxy derivative 15 in which the "meta" hydroxy group of the dopamine moiety is etherified.