127491-99-0

Basic information

• Product Name: (1RS,3S,5R)-3,5-bis(t-butyldimethylsiloxy)-1-carboethoxymethyl-2-methylenecyclohexane
• CAS NO: 127491-99-0
• Molecular Weight: 442.787
• Mol File: 127491-99-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (1RS,3S,5R)-3,5-bis(t-butyldimethylsiloxy)-1-carboethoxymethyl-2-methylenecyclohexane(CAS DataBase Reference)
• NIST Chemistry Reference: (1RS,3S,5R)-3,5-bis(t-butyldimethylsiloxy)-1-carboethoxymethyl-2-methylenecyclohexane(127491-99-0)
• EPA Substance Registry System: (1RS,3S,5R)-3,5-bis(t-butyldimethylsiloxy)-1-carboethoxymethyl-2-methylenecyclohexane(127491-99-0)

Safety Data

• Hazardous Substances Data: 127491-99-0(Hazardous Substances Data)

Upstream product

• 104464-04-2 (1S,4R,8S)-8-((S)-2-Methyl-1-phenyl-propoxy)-4-(toluene-4-sulfonyl)-2-oxa-bicyclo[2.2.2]oct-5-en-3-one 
• 127492-01-7 chiron 
• 104487-42-5 (4R,6S)-4-Hydroxy-6-((S)-2-methyl-1-phenyl-propoxy)-cyclohex-1-enecarboxylic acid methyl ester 
• 127492-00-6 (4R,6S)-4,6-Dihydroxy-cyclohex-1-enecarboxylic acid methyl ester 
• 99268-87-8 3-(p-toluenesulfonyl)-2-pyrone 
• 141803-99-8 (S)-6-Bromo-3,5-dihydroxy-hept-6-enoic acid ethyl ester 
• 141803-99-8 ethyl (3S,5S)-6-bromo-3,5-dihydroxyhept-6-enoate 
• 141804-00-4 ethyl (3S,5S)-3,5-bis(t-butyldimethylsiloxy)-6-bromohept-6-enoate 
• 141803-95-4 (+)-(4S)-3-<(2S,3S)-4-bromo-2-chloro-3-hydroxypent-4-enoyl>-4-isopropyl-2-oxazolinone 
• 141803-96-5 (+)-(4S)-<(3S)-4-bromo-3-hydroxypent-4-enoyl>-4-isopropyl-2-oxazolinone 
• 141803-98-7 (+)-ethyl (5S)-6-bromo-5-hydroxy-3-ketohept-6-enoate 
• 141803-97-6 (+)-(3S)-4-bromo-3-hydroxypent-4-enoic acid 
• 141847-49-6 (3S,5S)-3,5-bis(t-butyldimethylsiloxy)-6-bromohept-6-enal 
• 127492-02-8 (4R-trans)-4,6-Bis(tert-butyldimethylsiloxy)-1-cyclohexenemethanol 

Downstream Products

• 81506-23-2 <3S-(1E,3α,5β)>-<3,5-bis<<(1,1-dimethylethyl)dimethylsilyl>oxy>-2-methylenecyclohexylidene>acetic acid ethyl ester 
• 81570-20-9 <3S-(1Z,3α,5β)>-<3,5-bis<<(1,1-dimethylethyl)dimethylsilyl>oxy>-2-methylenecyclohexylidene>acetic acid ethyl ester 
• 161167-55-1 [(3S,5R)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-2-methylene-cyclohex-(Z)-ylidene]-acetic acid ethyl ester 

Relevant articles and documents

The Cyclization Route to the Calcitriol A-ring: A Formal Synthesis of (+)-1α,25-Dihydroxyvitamin D3

An efficient asymmetric synthesis of the A-ring of 1α,25-dihydroxyvitamin D3 from α-bromoacrolein is described.The key steps of the synthesis are the Evans type syn-selective asymmetric aldol reaction of bromoacrolein with the boron enolate of

Asymmetric total synthesis of an a-ring precursor to hormonally active 1α,25-dihydroxyvitamin D3

A new sulfinyl orthoester has been designed and used effectively in one-flask syntheses of dienoate esters from allylic alcohols; this new method as well as a highly stereocontrolled [2 + 4]-cycloaddition are applied to synthesis of 1α,25-dihydroxyvitamin D3.