128293-62-9

Basic information

• Product Name: ETHYL 4-AMINO-1-METHYL-1H-IMIDAZOLE-2-CARBOXYLATE
• Synonyms: ETHYL 4-AMINO-1-METHYL-1H-IMIDAZOLE-2-CARBOXYLATE;Ethyl 4-Amino-1-Methyl-1H-Imidazole-2-Carboxylate(WXC00021)
• CAS NO: 128293-62-9
• Molecular Formula: C₇H₁₁N₃O₂
• Molecular Weight: 169.18114
• EINECS: -0
• Mol File: 128293-62-9.mol
• Article Data: 18

Chemical Properties

• Boiling Point: 339.5±34.0 °C(Predicted)
• Appearance: /
• Density: 1.29±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C(protect from light)
• PKA: 4.43±0.60(Predicted)
• CAS DataBase Reference: ETHYL 4-AMINO-1-METHYL-1H-IMIDAZOLE-2-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 4-AMINO-1-METHYL-1H-IMIDAZOLE-2-CARBOXYLATE(128293-62-9)
• EPA Substance Registry System: ETHYL 4-AMINO-1-METHYL-1H-IMIDAZOLE-2-CARBOXYLATE(128293-62-9)

Safety Data

• Hazardous Substances Data: 128293-62-9(Hazardous Substances Data)

Usage

Description

ETHYL 4-AMINO-1-METHYL-1H-IMIDAZOLE-2-CARBOXYLATE is a chemical compound with the molecular formula C7H10N4O2, belonging to the imidazole and carboxylic acid derivatives. It is a white to off-white powder that is soluble in common organic solvents, making it suitable for various chemical reactions and formulations. ETHYL 4-AMINO-1-METHYL-1H-IMIDAZOLE-2-CARBOXYLATE is widely used in organic synthesis and medicinal chemistry, serving as a building block for pharmaceutical compounds, agrochemicals, and other industrial products. However, it is crucial to handle this compound with appropriate safety precautions due to potential health hazards if not properly managed.

Uses

Used in Pharmaceutical Industry:
ETHYL 4-AMINO-1-METHYL-1H-IMIDAZOLE-2-CARBOXYLATE is used as a building block for the development of pharmaceutical compounds. Its unique structure allows it to be incorporated into various drug molecules, potentially enhancing their therapeutic properties and effectiveness.
Used in Agrochemical Industry:
In the agrochemical industry, ETHYL 4-AMINO-1-METHYL-1H-IMIDAZOLE-2-CARBOXYLATE is used as a key component in the synthesis of agrochemicals. Its incorporation into these products can contribute to the development of more effective and targeted pest control solutions.
Used in Organic Synthesis:
ETHYL 4-AMINO-1-METHYL-1H-IMIDAZOLE-2-CARBOXYLATE is utilized as a versatile building block in organic synthesis. Its reactivity and solubility in common organic solvents make it an ideal candidate for the creation of a wide range of organic compounds for various applications.
Used in Industrial Product Development:
ETHYL 4-AMINO-1-METHYL-1H-IMIDAZOLE-2-CARBOXYLATE is also used in the development of other industrial products, where its unique chemical properties can be leveraged to improve product performance or create new applications. Its versatility and solubility make it a valuable asset in the development of innovative materials and formulations.

Upstream product

• 109012-23-9 ethyl 1-methyl-4-nitroimidazole-2-carboxylate 
• 30148-21-1 ethyl 1-methyl-1H-imidazole-2-carboxylate 

Downstream Products

• 128293-63-0 ethyl 4-tert-butyloxycarbonylamino-1-methylimidazole-2-carboxylate 
• 128293-69-6 C₁₅H₂₀N₆O₅ 
• 288625-59-2 ethyl 1-methyl-4-[p-bis(2-chloroethyl)aminobenzamido]-imidazole-2-carboxylate 
• 535937-76-9 1-methyl-4-[2-(4-trifluoromethyl-phenylsulfanyl)ethoxycarbonylamino]-1H-imidazole-2-carboxylic Acid Ethyl Ester 
• 454646-16-3 1-methyl-4-[2-(4-nitro-phenylsulfanyl)-ethoxycarbonylamino]-1H-imidazole-2-carboxylic acid ethyl ester 
• 292070-18-9 4-(4-tert-butoxycarbonylamino-benzoylamino)-1-methyl-1H-imidazole-2-carboxylic acid ethyl ester 
• 195387-59-8 4-[(4-tert-butoxycarbonylamino-1-methyl-1H-pyrrole-2-carbonyl)amino]-1-methyl-1H-imidazole-2-carboxylic acid ethyl ester 
• 454646-17-4 1-methyl-4-[2-(4-nitro-phenylsulfanyl)-ethoxycarbonylamino]-1H-imidazole-2-carboxylic acid 
• 535937-79-2 1-methyl-4-[2-(4-trifluoromethyl-phenylsulfanyl)-ethoxycarbonylamino]-1H-imidazole-2-carboxylic acid 
• 535937-85-0 1-methyl-4-[2-(4-trifluoromethyl-benzenesulfonyl)-ethoxycarbonylamino]-1H-imidazole-2-carboxylic acid 
• 292069-49-9 4-{[6-(3-tert-butoxycarbonylamino-benzoyl)-3,6,7,8-tetrahydro-3,6-diaza-as-indacene-2-carbonyl]-amino}-1-methyl-1H-imidazole-2-carboxylic acid ethyl ester 
• 292069-48-8 4-{[6-(4-tert-butoxycarbonylamino-benzoyl)-3,6,7,8-tetrahydro-3,6-diaza-as-indacene-2-carbonyl]-amino}-1-methyl-1H-imidazole-2-carboxylic acid ethyl ester 

Relevant articles and documents

Use of ferrocene scaffolds as pendant groups in hairpin-type pyrrole-imidazole polyamide molecules showing sequence-selective binding to DNA duplexes

The synthesis and properties of new conjugate molecules, Fc-PIA, composed of ferrocene (Fc) and pyrrole-imidazole polyamides (PIA) are reported. As a PIA sequence, we chose Im-Py-Im/Py-Im-Py considering its future application to the SNPs detection of gene

A Convenient Method for the Synthesis of DNA-Recognizing Polyamides in Solution

A convenient method for the synthesis of polyamides containing N-methylpyrrole (Py) and N-methylimidazole (Im) in solution has been developed. Most of the building blocks have been prepared by a haloform reaction in a simple way that column chromatography can be avoided. By use of the DCC/HOBT coupling reaction, the building blocks prepared have been effectively connected to construct a variety of subchains and polyamides without employing amino protection and deprotection. By use of the present method, an eight-ring polyamide, PyPyPyPyγPyImImPyβDp (γ is γ-aminobutyric acid, β is β-alanine, Dp is N,N-dimethylpropyldiamine), has been synthesized by the coupling of two four-ring subchains in one step.

SULFONIC ACID SALTS OF HETEROCYCLYLAMIDE-SUBSTITUTED IMIDAZOLES

The invention relates to sulfonic acid salts of heterocyclylamide-substituted imidazoles, and to solvates and hydrates thereof, to the use thereof for treating and/or preventing diseases, and to use thereof for producing drugs for treating and/or preventi

N-formamido-containing mono- and diheterocyclic pyrrole-and imidazole-2-carboxylic acids as building blocks for polyamide synthesis

Four N-formamido-containing mono-and diheterocyclic pyrrole- and imidazole-2-containing acids 1-4 were synthesized as intermediates for the preparation of polyamide molecules. The N-formamido-moiety forces the compounds to bind strongly as a stacked dimer, and in a staggered fashion, at specific sequences in the minor-groove of DNA. The acid moiety at the C-terminus of compounds enables these molecules to be coupled to amine-containing intermediates to form the amide linkages of the target polyamide. This convergent approach increases the synthetic diversity in polyamide chemistry by enabling one acid to be used with a variety of different C-terminus- functionalized intermediates. Copyright Taylor & Francis Group, LLC.